The Effect of Mesenchymal Stem Cell-Conditioned Medium Gel on Burn Wound Healing in Rats

    April 2022 in “ Veterinary world/Veterinary World ”
    Dian Ratih Laksmitawati, Siti Umrah Noor, Yati Sumiyati, Adrian Hartanto, Wahyu Widowati, Diah Kartika Pratami
    Image of study
    TLDR The mesenchymal stem cell-conditioned medium gel improved burn healing and hair growth in rats better than other treatments.
    This study investigated the effects of mesenchymal stem cell-conditioned medium (CM) gel on the healing of third-degree burns in rats. Twenty-four Sprague-Dawley rats with dorsal burn wounds were divided into four groups: one treated with CM gel, one with placebo gel, one with silver sulfadiazine (SSD) cream, and one without treatment, over a 21-day period. The study assessed wound healing through indicators such as wound diameter, scab and blister formation, and hair growth. Post-treatment analysis of the skin involved histological staining to evaluate neutrophil and mononuclear cell infiltration, neovascularization, collagen area, and re-epithelization ratio. The results showed that the CM gel group experienced better wound healing and faster hair growth compared to the other groups.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 13 results

      community Lavdik Hair Growth Serum?

      in Product 4 years ago
      A user is concerned about the legitimacy of a hair growth serum called Lavdik, which they ordered after seeing an ad for Jemros. The product contains ginger extract, ginseng extract, fleece flower root, grape seed oil, glycerol, carbomer, propylene glycol, and rosemary oil, and the user is unsure if it is effective or a scam.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

    Related Research

    1 / 1 results