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      research Alopecia Areata in Aging C3H/HeJ Mice

      178 citations , June 1994 in “Journal of Investigative Dermatology”
      Alopecia areata in these mice is inherited, more common in young females, and can be treated with triamcinolone acetonide.

      research Effects of Hyperbaric Oxygen Therapy on Rat Facial Skin

      2 citations , March 2015 in “Human & Experimental Toxicology”
      The study investigated the effects of hyperbaric oxygen (HBO) therapy on the facial skin of rats, revealing several histopathological changes. In the HBO-treated group (n = 6), there was evidence of epidermal hyperplasia and degeneration, basal-cell hypertrophy, and subepithelial fibrosis. The treatment led to reduced E-cadherin expression, indicating potential impairment of intracellular adhesion. Additionally, there was increased vimentin immunoreactivity and type IV collagen expression in the dermis, along with increased connective tissue, hemorrhage, and mononuclear cell infiltration. These findings suggested that HBO therapy significantly affected both the epidermal and dermal structures in rats.

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