Application of Cell-Derived Extracellular Vesicles and Engineered Nanovesicles for Hair Growth: From Mechanisms to Therapeutics

July 2022 in “ Frontiers in cell and developmental biology ”

Prakash Gangadaran, Ramya Lakshmi Rajendran, Mi Hee Kwack, Madhan Jeyaraman, Chae Moon Hong, Young Kwan Sung, Byeong‐Cheol Ahn

cell-derived nanovesicles extracellular vesicles proteins lipids nucleic acids endogenous materials exogenous drugs regenerative purposes hair growth hair loss CDVs EVs

TLDR Tiny natural vesicles from cells might help treat hair loss.

Recent studies have indicated that cell-derived nanovesicles (CDVs), which are natural extracellular vesicles capable of carrying biological materials like proteins, lipids, and nucleic acids, may offer new treatment strategies for hair growth. These vesicles can interact with cells both locally and at a distance, potentially delivering both endogenous materials and exogenous drugs for regenerative purposes. The review discusses the current understanding of how CDVs can be applied to hair growth and suggests that a deeper knowledge of their mechanisms could hasten their clinical application for treating hair loss.

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