TLDR Exosomes show promise for future tissue regeneration.
Exosomes, small vesicles released by various cell types, are gaining attention in regenerative medicine for their role in intercellular communication and therapeutic potential. They transfer biomolecules like proteins, lipids, and RNA between cells, which can enhance or impair biological functions. This paper reviews the origins, properties, and applications of exosomes, highlighting their structural, biological, physical, and chemical aspects. It also discusses recent advancements in tissue repair and regenerative medicine, emphasizing the potential of exosomes in future tissue regeneration efforts.
19 citations
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January 2023 in “Frontiers in Bioengineering and Biotechnology” MSC-sEVs may effectively treat chronic non-healing wounds.
72 citations
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
220 citations
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March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
May 2025 in “International Journal of Molecular Sciences” Exosomes from rat hair follicle stem cells may help heal wounds and regenerate skin.
January 2025 in “Cosmetics” Exosomes could improve skin care, but more research is needed to confirm their safety and effectiveness.
September 2025 in “Stem Cells Translational Medicine” Lithium chloride-treated stem cell exosomes boost hair growth by activating a specific pathway.
February 2024 in “Skin health and disease” Exosomes could improve skin and hair treatments but are limited by cost, production difficulty, and need for more research.
1 citations
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June 2023 in “Cells” Exosomes could be a promising way to help repair skin and treat skin disorders.
