Exosomes and Their Bioengineering Strategies in Cutaneous Wound Healing and Related Complications: Current Knowledge and Future Perspectives

    Guang Yang, Saquib Waheed, Cong Wang … Jun Wu
    Studysummary This review discusses recent advances in the therapeutic potential of exosomes for wound healing, highlighting their benefits and challenges but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 16

    1. Bio-Pulsed Stimulation Effectively Improves the Production of Avian Mesenchymal Stem Cell-Derived Extracellular Vesicles That Enhance the Bioactivity of Skin Fibroblasts and Hair Follicle Cells International journal of molecular sciences · 2022
    2. Type 2 Diabetes Mellitus Inhibits Skin Renewal Through Inhibiting WNT-Dependent Lgr5+ Hair Follicle Stem Cell Activation in C57BL/6 Mice Journal of diabetes research · 2022
    3. Exosomal miRNA-181a-5p from Hair Follicle Dermal Papilla Cells Promotes Hair Follicle Growth and Development via the Wnt/β-Catenin Signaling Pathway International journal of biological macromolecules · 2022
    4. Skin Cell-Derived Extracellular Vesicles: A Promising Therapeutic Strategy for Cutaneous Injury Burns and trauma · 2022
    5. Exosomes Derived From Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation Through The Wnt3a/Beta-Catenin Signaling Pathway Oxidative Medicine and Cellular Longevity · 2022
    6. Stem Cell Therapy for Burns: The Story So Far Biologics · 2021
    7. Human Amniotic Fluid Stem Cell-Derived Exosomes as a Novel Cell-Free Therapy for Cutaneous Regeneration Frontiers in Cell and Developmental Biology · 2021
    8. Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion Nutrients · 2021
    9. Obstruction of Granulation Tissue Formation Leads to Delayed Wound Healing After Scald Burn Injury in Mice Burns & Trauma · 2021
    10. Wound Healing: Cellular Mechanisms and Pathological Outcomes Open Biology · 2020
    11. Platelet Sonicates Activate Hair Follicle Stem Cells And Mediate Enhanced Hair Follicle Regeneration Journal of Cellular and Molecular Medicine · 2019
    12. Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation International journal of biological sciences · 2019
    13. LL-37 Stimulates the Functions of Adipose-Derived Stromal/Stem Cells via Early Growth Response 1 and the MAPK Pathway Stem cell research & therapy · 2016
    14. Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications International journal of molecular sciences · 2015
    15. Hair Follicle and Interfollicular Epidermal Stem Cells Make Varying Contributions to Wound Regeneration Cell Cycle · 2015
    16. An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007