Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications

October 2015 in “ International journal of molecular sciences ”

Nkemcho Ojeh, Irena Pastar, Marjana Tomić-Canić, Olivera Stojadinović

stem cells epidermal stem cells hair follicles skin regeneration wound healing skin homeostasis chronic wounds skin integrity damaged tissue adult stem cells skin disorders cutaneous repair skin tissue-engineered products

TLDR Stem cells are crucial for skin repair and new treatments for chronic wounds.

The document discussed the critical role of stem cells in skin homeostasis, regeneration, and wound healing. It highlighted that stem cells in the epidermis and hair follicles are essential for maintaining skin integrity and repairing damaged tissue. Chronic wounds often result from stem cell depletion and other poorly understood mechanisms, and current therapies are limited. The review explored the potential of adult stem cells, particularly epidermal stem cells, in developing new therapeutic strategies for non-healing wounds and other skin disorders. It also examined how skin tissue-engineered products could be optimized for better cutaneous repair and regeneration.

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