Advances in Skin Grafting and Treatment of Cutaneous Wounds

    November 2014 in “ Science ”
    Bryan K. Sun, Zurab Siprashvili, Paul A. Khavari
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    TLDR Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.
    The 2014 document "Advances in skin grafting and treatment of cutaneous wounds" reviewed the process of cutaneous wound healing and the role of various cells in this process. It emphasized the potential of stem cells, particularly those in the hair follicle bulge, in wound repair. The document also discussed the use of recombinant human platelet-derived growth factor for treating lower extremity ulcers and the potential of gene and stem cell therapy in treating cutaneous wounds. It mentioned the use of genetically modified epidermal stem cells in treating a severe skin condition called junctional epidermolysis bullosa. The document concluded that while there have been significant advances in the field of skin grafting and wound treatment, more research is needed to fully understand wound healing mechanisms and develop more effective treatments.
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