A Pilot Clinical Study of Hair Grafting in Chronic Leg Ulcers

    October 2012 in “ Wound Repair and Regeneration ”
    Francisco Jiménez, C Garde, Enrique Poblet, Begoña Jimeno, Jesús Ortiz, María Luisa Martínez, Araika Gutiérrez‐Rivera, Virginia Pérez‐López, Usue Etxaniz, Corina Naveda, José L. Higuera, Nerea Egüés, Eduardo Escario, Ander Izeta
    Studysummary This study found that transplanting autologous scalp follicular grafts into chronic leg ulcers led to a greater reduction in ulcer size compared to non-grafted areas, suggesting a promising therapeutic alternative. Our plain-language summary of this paper — not a Tressless recommendation.
    This pilot clinical study investigated the feasibility and healing potential of autologous scalp follicular grafts in treating chronic leg ulcers. The study included 10 patients with ulcers averaging 36.8 cm² in size and lasting 10.5 years. Each ulcer had a 2×2 cm "experimental" square that received 20 hair grafts and a control square that did not. After 18 weeks, the experimental squares showed a 27.1% reduction in ulcer area compared to a 6.5% reduction in the control squares, with significant improvements in epithelialization, neovascularization, and dermal reorganization. The study concluded that hair follicle grafting is a safe and promising outpatient treatment for nonhealing chronic leg ulcers.
    Discuss this study in the Community →

    Research cited in this study

    7 / 7 results