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GlossaryCRISPR (CRISPR gene editing)

gene-editing tool that precisely alters DNA sequences

CRISPR, which stands for Clustered Regularly Interspaced Short Palindromic Repeats, is a revolutionary gene-editing technology that allows scientists to precisely alter DNA sequences within organisms. It utilizes the Cas9 protein to cut DNA at specific locations, enabling the addition, removal, or modification of genetic material, which has vast implications for treating genetic disorders, improving crops, and advancing biological research.

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research Progress in Research and Prospects for Application of Precision Gene-Editing Technology Based on CRISPR-Cas9 in the Genetic Improvement of Sheep and Goats

March 2024 in “Agriculture”

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

research Spatiotemporal Control of CRISPR/Cas9 Gene Editing

51 citations, June 2021 in “Signal Transduction and Targeted Therapy”

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

research Stimuli-Responsive Nanoformulations for CRISPR-Cas9 Genome Editing

7 citations, August 2022 in “Journal of Nanobiotechnology”

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

research Revolutionary Approaches to Hair Regrowth: Follicle Neogenesis, Wnt/β-Catenin Signaling, and Emerging Therapies

May 2025 in “Cells”

New hair regrowth therapies show promise but need more research.

research Tailored Chromatin Modulation to Promote Tissue Regeneration

10 citations, May 2019 in “Seminars in Cell & Developmental Biology”

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

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community Some common misconceptions about why there have been no breakthroughs in treatments for so long and why a one and done cure is almost impossible.

in Treatment 52 upvotes 1 week ago

Developing new hair loss treatments is challenging due to the complexity and cost of trials, and a permanent cure is unlikely soon. Current treatments like Minoxidil and finasteride are used continuously because hair loss is progressive, and future possibilities include gene editing and hair cloning.

community When are we getting a cure to hair loss?

in Chat 2 years ago

Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

community (Serious) News and discussion on potential treatments

in Treatment 28 upvotes 6 months ago

Current hair loss treatments include finasteride, dutasteride, minoxidil, and derma rolling. New treatments like TDM-105795, GT20029, and others show promise but require more testing and time before approval.

community What should we lookout for in the near future for hairloss?

in Research/Science 17 upvotes 1 year ago

The user is using finasteride and minoxidil for hair loss but is looking for new treatments. Pyrilutamide and GT20029 are potential future treatments, with Pyrilutamide expected next year and GT20029 possibly by 2027.

community Had a son while being on FIN, MUST READ

in Finasteride/Dutasteride 619 upvotes 1 year ago

A user shared his experience of having two healthy children while continuously using finasteride (Fin) for hair loss, challenging fears about its potential impact on fetal development. The discussion that followed included various perspectives, with some users sharing similar experiences, others expressing concerns about potential risks, and some emphasizing the need for more substantial evidence before drawing conclusions.

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