Efficient Gene Editing for Heart Disease via ELIP-Based CRISPR Delivery System

    February 2024 in “ Pharmaceutics ”
    Xing Yin, Romain Harmancey, Brion Frierson … Shaoling Huang
    Studysummary This study found that echogenic liposomes improved the delivery and penetration of CRISPR/Cas9 genetic materials into cardiomyocytes, both in vitro and in vivo, especially when combined with ultrasound, highlighting a promising strategy for cardiovascular gene therapy.
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    Research cited in this study 2

    1. Liposome-Based Carriers for CRISPR Genome Editing International Journal of Molecular Sciences · 2023
    2. Ultrasound-Activated Particles as CRISPR/Cas9 Delivery System for Androgenic Alopecia Therapy Biomaterials · 2019