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GlossaryCRISPR (CRISPR technology)

gene-editing tool that precisely alters DNA sequences

CRISPR, which stands for Clustered Regularly Interspaced Short Palindromic Repeats, is a revolutionary gene-editing technology that allows scientists to precisely alter DNA sequences within organisms. It utilizes the Cas9 protein to cut DNA at specific locations, enabling the addition, removal, or modification of genetic material, which has vast implications for treating genetic disorders, improving crops, and advancing biological research.

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research Progress in Research and Prospects for Application of Precision Gene-Editing Technology Based on CRISPR-Cas9 in the Genetic Improvement of Sheep and Goats

March 2024 in “Agriculture”

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

research Liposome-Based Carriers for CRISPR Genome Editing

August 2023 in “International Journal of Molecular Sciences”

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

research Development of an Intrinsic Skin Sensor for Blood Glucose Level with CRISPR-Mediated Genome Editing in Epidermal Stem Cells

April 2017 in “Journal of Investigative Dermatology”

Researchers created a skin graft that senses blood glucose and could treat diabetes using CRISPR-edited stem cells.

research Melanocytes in Regenerative Medicine Applications and Disease Modeling

April 2024 in “Journal of translational medicine”

Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.

Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders

research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders

November 2023 in “ACS Omega”

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

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community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 1 month ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community FtM: "Aggressive Regemin - Recovery From Norwood-6.5" Minoxodil/Estradiol valerate/Spironolactone. (What will happen in the worst case if CIS male go this way for a year?)

in Progress Pictures 54 upvotes 3 years ago

User "Ant1pal" shares progress pictures of hair regrowth using Minoxidil, Estradiol valerate, and Spironolactone. Users discuss potential side effects and the possibility of localizing estrogen to hair follicles for better treatment.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 22 upvotes 3 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community 22 years since the last major development

in Technology 50 upvotes 3 years ago

The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.

community When are we getting a cure to hair loss?

in Chat 1 year ago

Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

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