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    A Skin Organoid-Based Infection Platform Identifies an Inhibitor Specific for Hand, Foot, and Mouth Disease

    March 2025 in “ Nature Communications
    Jun Li, Jie Ma, Ruiyuan Cao … Ling Leng
    Studysummary This study used human stem cell-derived skin organoids to model EV-A71 infection, revealing that various skin cell types are susceptible to the virus and identifying a potential drug target and replication inhibitor, suggesting its utility for studying skin infectious diseases and drug screening.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 2

    1. Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells Nature · 2020
    2. Molecular Mechanisms of Viral Oncogenesis in Humans Nature Reviews Microbiology · 2018