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Glossary Topical Steroid

medication applied to skin to reduce inflammation and immune response

A topical steroid, also known as a topical corticosteroid, is a medication applied directly to the skin to reduce inflammation and suppress the immune response. It is commonly used to treat conditions like eczema, psoriasis, and alopecia areata by decreasing redness, swelling, and itching.

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Research

5 / 1000+ results

research Systemic Steroids With or Without 2% Topical Minoxidil in the Treatment of Alopecia Areata

101 citations , November 1992 in “Archives of Dermatology”

In this study, tapering prednisone followed by 2% topical minoxidil helped limit hair loss in some patients with alopecia areata, with 30% to 47% showing over 25% hair regrowth initially.

research THERAPEUTIC HOTLINE: Effectiveness of the association of cetirizine and topical steroids in lichen planus pilaris - an open-label clinical trial

9 citations , September 2010 in “Dermatologic therapy”

This study found that combined therapy with cetirizine and topical steroids stabilized inflammation in most patients with lichen planus pilaris, though one patient experienced cardiac arrhythmia.

research The use of biodegradable microneedle patches to increase penetration of topical steroid for prurigo nodularis.

5 citations , January 2018 in “PubMed”

In this study, applying a biodegradable microneedle patch after topical steroid application significantly increased steroid penetration and improved treatment outcomes in patients with prurigo nodularis compared to the control.

research High‐Potency Topical Steroids: An Effective Therapy for Chronic Scalp Inflammation in Rapp–Hodgkin Ectodermal Dysplasia

3 citations , February 2016 in “Pediatric dermatology”

This report describes two cases of Rapp–Hodgkin ectodermal dysplasia where refractory scalp erosions improved significantly with potent topical steroids; it also suggests a potential link between these scalp conditions and erosive pustular dermatosis of the scalp in elderly patients.

research Ingestion of topical steroid triggering pustular psoriasis?

1 citations , August 2005 in “British Journal of Dermatology”

This case report describes a 7-year-old girl who developed widespread erythroderma and systemic symptoms after ingesting clobetasone butyrate cream, despite previous psoriasis treatment.

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Community Join

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community I always hear the advice to reduce scalp inflammation. What are some non-steroidal ways to reduce inflammation?

in Treatment 13 upvotes 1 year ago

Non-steroidal ways to reduce scalp inflammation include using topical melatonin, urea shampoo, Zyrtec, turmeric with black pepper, omega-3 supplements, a self-made topical solution with cetirizine, melatonin, and piroctone olamine, ketoconazole shampoo, witch hazel shampoo, tacrolimus, and lifestyle changes like a healthy diet and regular exercise. Some users also mentioned unconventional methods like infrared light therapy and a carnivore diet.

community Custom topical from Rootsbyga.

in Treatment 4 upvotes 1 year ago

A user received a custom topical treatment for hair loss from Rootsbyga, which includes minoxidil and possibly other ingredients to enhance its effectiveness. The initial test cost $120, and the monthly topical costs around $70, with concerns about long-term use of steroids like hydrocortisone.

community How to Keep Your Hair on Steroids

25 upvotes 2 years ago

To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

community Finasteride does deplete important nuero-active steroids

11 upvotes 3 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

community Women complaining of bad effects from Winlevi (Clascoterone 1%)

11 upvotes 9 months ago

Women experienced severe reactions, including Topical Steroid Withdrawal (TSW), from using Winlevi (Clascoterone 1%) on their faces. Concerns were raised about the potential risks of higher concentrations, especially for hair loss treatment.

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Learn

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learn Hydrocortisone

a synthetic cortisol used for anti-inflammatory effects

When should hydrocortisone be used for hair loss — is it only for irritated scalps or also alopecia areata? Hydrocortisone is a low-potency topical steroid whose labelled use is calming scalp irritation such as dermatitis; for alopecia areata no verified human trial supports it on its own, and dermatologists generally use stronger prescription corticosteroids instead.
Is hydrocortisone effective for stopping inflammation that blocks hair growth? Sources describe hydrocortisone as a short-course treatment for scalp inflammation such as seborrhoeic dermatitis or eczema, and no verified trial tests it as a hair-regrowth treatment; the corticosteroids used for alopecia areata are the potent prescription ones, and prolonged use of any topical steroid on the scalp risks skin thinning.

learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

learn Fluocinolone

Can long-term use of Fluocinolone affect the health of hair follicles? There is no long-term human trial measuring what topical fluocinolone does to hair follicles; what is documented is the label's warning about skin atrophy with prolonged use, plus a 2007 mouse study suggesting hair-follicle bulge stem cells do not repair steroid-induced atrophy.

learn Bimatoprost

What do the latest studies say about bimatoprost for scalp hair growth? Bimatoprost is approved only for eyelashes; a 30-person pilot found it beat a topical steroid on patches of alopecia areata, but the two registered Allergan trials in male pattern hair loss were never published and never taken further, so scalp use stays off-label and experimental.

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

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