Clinical Applications of Antiandrogens

October 1988 in “ Journal of Steroid Biochemistry ”

M. Namer

antiandrogens cyproterone acetate flutamide anandron hirsutism alopecia acne steroidal antiandrogens non-steroidal antiandrogens topical antiandrogens Androcur Eulexin Nilutamide

Studysummary This review discusses the use of antiandrogens for various conditions like prostate cancer and highlights their potential benefits in remission rates and symptom improvement, but it reports no new clinical results.

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Research cited in this study

8 / 8 results

research A Comparative Study of Aldactone and Diane in the Treatment of Hirsutism

20 citations , August 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”

This study suggests that Aldactone may be more effective than Diane in reducing hair growth, despite having minimal impact on hormone levels.

research Pharmacology of Antiandrogens

97 citations , November 1986 in “Journal of Steroid Biochemistry”

This review discusses the pharmacological properties and clinical applications of cyproterone acetate and similar antiandrogens, noting previous failures in local applications due to concentration limitations; it reports no new empirical results.

research Regulation of Androgen Receptor and 5α-Reductase in the Skin of Normal and Hirsute Women

35 citations , May 1986 in “Clinics in endocrinology and metabolism”

This study concludes that high skin 5α-reductase activity may contribute to hirsutism, but the specific regulatory mechanisms and genetic factors remain unclear.

research Treatment of Hirsutism and Acne with Cyproterone Acetate

43 citations , May 1986 in “Clinics in Endocrinology and Metabolism”

This review examines androgen status in male and female obesity and its influence on the metabolic syndrome, but reports no new clinical results.

research The Stimulation of Hair Growth in the Flank Organs of Female Hamsters by Subcutaneous Testosterone Propionate and Its Inhibition by Topical Cyproterone Acetate: Dose-Response Studies

15 citations , November 1983 in “British journal of dermatology/British journal of dermatology, Supplement”

This study found that testosterone propionate increased hair mass in female hamsters' flank organs, while cyproterone acetate applied topically reduced androgen-stimulated hair in a dose-dependent manner.