The Stimulation of Hair Growth in the Flank Organs of Female Hamsters by Subcutaneous Testosterone Propionate and Its Inhibition by Topical Cyproterone Acetate: Dose-Response Studies

    November 1983 in “ British journal of dermatology/British journal of dermatology, Supplement ”
    Edwin Kaszynski
    TLDR Testosterone increases hamster hair growth; cyproterone acetate reduces it.
    In the 1983 study, 11-week-old female hamsters experienced a dose-dependent increase in the mass of hair in their flank organs following subcutaneous injections of testosterone propionate. Additionally, when cyproterone acetate, an anti-androgen, was applied topically to one flank organ of each hamster, there was a bilateral and dose-dependent decrease in the mass of the androgen-stimulated hair. This suggests that testosterone propionate can stimulate hair growth, while cyproterone acetate can inhibit this effect. The number of hamsters involved in the study was not specified in the summary provided.
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