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Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

This review discusses the roles of hair follicles and sebaceous glands in percutaneous transport and reports no new results, noting a lack of adequate models and methodologies.

This review examines the role of hair follicles and sebaceous glands in percutaneous drug delivery but does not report new clinical results; it calls for further exploration of follicle-targeting therapies.

In this study, ethosomes were more effective than liposomes for delivering finasteride through human skin, showing higher transdermal flux and accumulation, especially in deeper skin layers.

This study found that adapalene-loaded microemulsions significantly enhanced the drug's penetration through guinea pig skin compared to an aqueous suspension, with factors like surfactant ratios and the water-oil phase balance affecting the transfollicular drug delivery efficiency.