Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle

    October 2002 in “ Journal of controlled release ”
    Ylva Y. Grams, Joke A. Bouwstra
    Studysummary This study found that increasing a drug's lipophilicity and adding ethanol to the donor phase can enhance its delivery to the hair follicle, although the precise transport mechanism remains unclear.
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    Research cited in this study 4

    1. Enhanced Delivery of Drugs Into and Across the Skin by Ethosomal Carriers Drug Development Research · 2000
    2. Evaluation of the Hairless Rat as a Model for In Vivo Percutaneous Absorption Journal of Pharmaceutical Sciences · 1997
    3. Relative Influence of Ethanol and Propylene Glycol Cosolvents on Deposition of Minoxidil into the Skin Journal of Pharmaceutical Sciences · 1994
    4. Role of Transepidermal and Transfollicular Routes in Percutaneous Absorption of Steroids: In Vitro Studies on Human Skin Skin Pharmacology and Physiology · 1994