Effect of Charge Carrier Lipid on Skin Penetration, Retention, and Hair Growth of Topically Applied Finasteride-Containing Liposomes

    April 2011 in “ Biomolecules & Therapeutics ”
    Sang-im Lee, Santhosh Kumar, Nagayya Sriraman … Bong Kyu Yoo
    Studysummary This study found that finasteride-containing anionic liposomes enhanced skin retention and had moderate hair growth efficacy, suggesting potential for treating androgenetic alopecia with reduced systemic side effects.
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    Research cited in this study 10

    1. Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia Archives of Dermatology · 2010
    2. In Vitro Percutaneous Permeation and Skin Accumulation of Finasteride Using Vesicular Ethosomal Carriers Aaps Pharmscitech · 2008
    3. Androgenetic Alopecia: Clinical Features, Classification, and Treatments Endocrinology and Metabolism Clinics of North America · 2007
    4. The Influence of Selected Steroid Hormones on the Physicochemical Behavior of DPPC Liposomes Chemistry and Physics of Lipids · 2007
    5. Development of Liposomal Systems of Finasteride for Topical Applications: Design, Characterization, and In Vitro Evaluation Pharmaceutical Development and Technology · 2007
    6. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006
    7. Simultaneous Effects of Tocopheryl Polyethylene Glycol Succinate on Local Hair Growth Promotion and Systemic Absorption of Topically Applied Minoxidil in a Mouse Model International Journal of Pharmaceutics · 2005
    8. Skin Permeation of Different Steroid Hormones from Polymeric Coated Liposomal Formulations European journal of pharmaceutics and biopharmaceutics · 2005
    9. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992
    10. Metabolism of Androgens by Isolated Human Hair Follicles Journal of Steroid Biochemistry · 1972

    Related research 4

    1. Influence of Massage and Occlusion on the Ex Vivo Skin Penetration of Rigid Liposomes and Invasomes European journal of pharmaceutics and biopharmaceutics · 2013
    2. Effect of Charge Carrier Lipid on Skin Penetration, Retention, and Hair Growth of Topically Applied Finasteride-Containing Liposomes Biomolecules & Therapeutics · 2011
    3. Study on Transdermal Permeation and Skin Accumulation of Finasteride Ethosomes Zhōnghuá yàoxué zázhì · 2004
    4. Finasteride and the Hair Cycle Journal of The American Academy of Dermatology · 2000