Skin Permeation of Different Steroid Hormones from Polymeric Coated Liposomal Formulations

    October 2005 in “ European journal of pharmaceutics and biopharmaceutics ”
    Babette Biruss, Claudia Valenta
    Studysummary This study found that polymers significantly improved the chemical and microbial stability of steroid hormones in liposome formulations over eight weeks, with finasteride showing the highest diffusion rate.
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    Research cited in this study 6

    1. A Stability-Indicating HPLC Method to Determine Finasteride in a Tablet Formulation Journal of Liquid Chromatography & Related Technologies · 2002
    2. LC Determination of Finasteride and Its Application to Storage Stability Studies Journal of Pharmaceutical and Biomedical Analysis · 2001
    3. New Topical Antiandrogenic Formulations Can Stimulate Hair Growth in Human Bald Scalp Grafted Onto Mice International Journal of Pharmaceutics · 2000
    4. In Vivo Time-Dependent Inhibition of Human Steroid 5α-Reductase by Finasteride Journal of Pharmaceutical Sciences · 1996
    5. Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity Journal of Investigative Dermatology · 1995
    6. Finasteride: A Slow-Binding 5-Alpha-Reductase Inhibitor Biochemistry · 1993

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    8. Finasteride Inhibits 5α-Reductase Activity in Human Dermal Fibroblasts: Prediction of Its Therapeutic Application in Androgen-Related Skin Diseases International Journal of Dermatology · 1995