TLDR New method quickly and accurately measures finasteride in tablets.
This document describes a validated HPLC method for determining the amount of finasteride in a tablet formulation. The method was found to be simple, rapid, reproducible, economic, and stability-indicating. The accuracy of the assay was assessed at 80, 100, and 120% of finasteride by recovery experiments, using tablets from the same lot of a commercial formulation. The method was developed by evaluating the effect of mobile phase proportion on retention time and tailing factor, and precision was considered at two levels of ICH suggestions: repeatability and intermediate precision.
823 citations
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February 1998 in “Analytical Chemistry” Method detects finasteride in plasma at very low concentrations.
17 citations
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May 1997 in “Journal of Chromatography B: Biomedical Sciences and Applications” Method accurately measures finasteride in human plasma.
29 citations
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February 1996 in “Journal of Chromatography B: Biomedical Sciences and Applications” New method detects finasteride in plasma quickly and accurately without clean-up.
45 citations
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August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications” Method detects finasteride in plasma and semen with high sensitivity and accuracy.
19 citations
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May 1991 in “Journal of Chromatography B: Biomedical Sciences and Applications” Reliable method detects finasteride in human plasma at low doses.
5 citations
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February 2013 in “Journal of Liquid Chromatography & Related Technologies” Method accurately measures finasteride concentration in medicine.
1 citations
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December 2009 in “Asian Journal of Research in Chemistry” The methods accurately measure Finasteride and Tamsulosin in tablets.
1 citations
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January 2017 in “Asian Journal of Chemistry” New method effectively analyzes finasteride and its stability.
April 2018 in “Journal of Chromatographic Science” Finasteride's stability and safety confirmed through precise analytical methods.
November 2023 in “Acta scientific pharmaceutical sciences” Different methods accurately measure Finasteride in medicines and body fluids.
4 citations
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January 2013 in “Dissolution Technologies” A method was developed to test the breakdown of Finasteride capsules, showing it can tell the difference between different brands and highlighting the need for standard tests and ingredient consistency.
