Advancements in Regenerative Medicine for Aesthetic Dermatology: A Comprehensive Review and Future Trends

    March 2024 in “ Cosmetics
    Federica Trovato, S. Ceccarelli, Simone Michelini, Giordano Vespasiani, Stefania Guida, Hassan Galadari, Steven Paul Nisticò, Laura Colonna, Giovanni Pellacani
    TLDR New regenerative techniques show promise for improving skin, healing wounds, and growing hair.
    The review "Advancements in Regenerative Medicine for Aesthetic Dermatology" discusses the latest developments in regenerative techniques such as adipose-derived stem cells (ASCs), nanofat grafting, platelet-rich plasma (PRP), and extracellular vesicles (EVs). These methods show promise in skin regeneration, wound healing, and hair growth. For instance, nanofat grafting has improved skin quality in studies with 50 patients, and PRP has shown superior results in treating alopecia areata in a study with 45 patients. The review emphasizes the potential of these therapies while noting challenges like donor site morbidity and variability in graft survival, suggesting a need for more in vivo trials and a multi-target, sequential therapeutic strategy to enhance clinical outcomes.
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