Nanofat in Plastic Reconstructive, Regenerative, and Aesthetic Surgery: A Review of Advancements in Face-Focused Applications

    June 2023 in “ Journal of clinical medicine ”
    Simone La Padula, Martina Ponzo, Michele Lombardi, Vincenzo Iazzetta, Concetta Errico, Gianpiero Polverino, Francesca Russo, Luca D’Andrea, Barbara Hersant, Jean Paul Meningaud, Giovanni Salzano, Rosita Pensato
    TLDR Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.
    Nanofat, derived from mechanically emulsified adipose tissue, shows promise in plastic, reconstructive, regenerative, and aesthetic surgery, particularly for facial applications. It improves skin quality, treats scars, and rejuvenates aged skin by leveraging adipose-derived stem cells (ASCs) and growth factors. Studies, including those with 67 and 50 patients, report significant improvements in skin texture, elasticity, and radiance, with minimal side effects and high patient satisfaction. Despite these positive outcomes, further research is needed to standardize protocols and evaluate long-term efficacy and safety.
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