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GlossaryAdult Stem Cells (ASCs)

undifferentiated cells in adults that regenerate specific tissues

Adult stem cells, also known as somatic stem cells, are undifferentiated cells found throughout the body after development. They have the ability to self-renew and differentiate into various specialized cell types of the tissue or organ they reside in, playing a crucial role in tissue repair and regeneration. Unlike embryonic stem cells, adult stem cells are limited in their differentiation potential but are less likely to cause ethical concerns or immune rejection when used in therapies.

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Differential Molecular Signature of Dermal Papilla Cells from Balding and Non-Balding Scalp in 2D, 3D Culture and Co-Culture with Adipose-Derived Stem Cells

research Differential Molecular Signature of Dermal Papilla Cells from Balding and Non-Balding Scalp in 2D, 3D Culture and Co-Culture with Adipose-Derived Stem Cells

September 2019 in “Journal of Investigative Dermatology”

Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.

research Systematic Review: Allogenic Use of Stromal Vascular Fraction and Decellularized Extracellular Matrices as Advanced Therapy Medicinal Products in Tissue Regeneration

113 citations , July 2020 in “International Journal of Molecular Sciences”

Allogenic ASCs and ECM transplants are safe and effective for tissue regeneration.

research Exploring the Role of Stem Cells in Cutaneous Wound Healing

222 citations , August 2009 in “Experimental Dermatology”

Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.

research Adipose-Derived Cellular and Cell-Derived Regenerative Therapies in Dermatology and Aesthetic Rejuvenation

60 citations , June 2019 in “Ageing Research Reviews”

Fat from the body can help improve hair growth and scars when used in skin treatments.

research LL-37 Stimulates the Functions of Adipose-Derived Stromal/Stem Cells via Early Growth Response 1 and the MAPK Pathway

53 citations , April 2016 in “Stem cell research & therapy”

LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.

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community Il PP405 è molto promettente ma non è l'unico in grado di liberarci dalla iattura

in Research/Science 3 upvotes 2 months ago

PP405 shows promise in hair loss treatment, but stem cell therapy using adipose-derived stem cells and ATP also successfully reversed androgenetic alopecia in mice. Stem cell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.

community Dont stop using Minoxidil i beg you! Dont be fool like me.

in Minoxidil 507 upvotes 1 year ago

Stopping minoxidil causes significant hair loss, as continued use is necessary for maintaining gains. Combining minoxidil with finasteride may help maintain hair, but both treatments are typically lifelong commitments.

community Why is Minoxidil not enough for hair loss? (No fin)

in Minoxidil 57 upvotes 11 months ago

Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.