Advances in the Use of Platelet-Rich Plasma and Adipose Tissue Derivatives in Surgical Regenerative Medicine

This review highlights the promising role of adipose-derived tissues and platelet-rich plasma (PRP) in regenerative medicine and aesthetic surgery, emphasizing their ability to stimulate tissue repair, enhance angiogenesis, and reduce inflammation. The combination of PRP with fat grafts has shown improved graft retention and healing outcomes, particularly in facial reconstruction, wound healing, and breast surgery. Despite the demonstrated benefits, the review notes that variability in preparation methods and application protocols limits the comparability of studies. It calls for further research to standardize techniques and validate outcomes to expand the clinical use of these therapies.