Biological Roles and Prospects of Using Adipose Tissue Derivatives and Platelet-Rich Plasma in Surgical Practice: A Review

This study evaluated the feasibility of a single-center, three-arm trial to assess fat grafting with or without PRP for diabetic foot ulcers, finding high patient engagement and indicating that a multi-center trial could be safe and feasible.

This study's meta-analysis reported that PRP injections significantly increased hair density compared to baseline and placebo in androgenetic alopecia patients, supporting its use as a beneficial treatment.

In a porcine model, this study observed that using an External Tissue Expansion Device increased epidermis thickness, cell proliferation, and vessel density at fat graft recipient sites.

This review assesses the use of platelet-rich plasma in dermatology and concludes that while there may be modest benefits for certain conditions, more evidence is needed before it can be widely recommended.

This study found that platelet-rich plasma injections significantly increased hair count and density in patients with male pattern hair loss without major side effects, suggesting it may be a safe and effective treatment option.

This review discusses the increased use of platelet-rich plasma in dermatology for conditions like skin ulcers and alopecia but reports no new clinical results, emphasizing the need for more scientific evidence to support its benefits.