Biologically Driven Innovations in Aesthetic Surgery: Advances in Regenerative and Cellular Therapies

    November 2025 in “ IECCMEXICO ”
    Yahir Oliver Balderas, Wilmer Giovanny Galvis Ballesteros, Jorge Luis Rodríguez Olguín, Sneyder Mauricio Quitiaquez Figueroa, David Alberto Díaz Paipa, María Edilia Oballe Salazar, Jean Carlo Franco Salas, Jesús Ricardo Jiménez López
    From the encyclopedia
    Platelet-Rich Plasma →

    growth factors taken from your blood and injected into your scalp to stimulate hair

    Exosomes →

    Microscopic delivery system that sends growth-promoting signals to hair follicles

    Image
    Studysummary This review found that adipose-derived stem cells and stromal vascular fraction have robust clinical benefits in aesthetic surgery, particularly in facial rejuvenation, scar treatment, and volumetric restoration, with favorable safety profiles. Our plain-language summary of this paper — not a Tressless recommendation.
    Regenerative and cellular therapies are transforming aesthetic surgery by using biologically driven methods to enhance tissue quality and clinical outcomes. This review highlights the effectiveness of adipose-derived stem cells (ADSCs) and stromal vascular fraction (SVF) in promoting angiogenesis, reducing inflammation, and remodeling the extracellular matrix, making them dominant in facial rejuvenation and scar treatment. Platelet-rich plasma (PRP) is beneficial for improving skin texture and healing, while non-adipose mesenchymal stem cells (MSCs) have limited use due to regulatory issues. Despite the promising results, challenges remain in standardizing preparation protocols and conducting long-term studies. Future advancements will rely on standardized techniques and new biotechnologies like exosomes, emphasizing natural outcomes and personalized care.
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