Biologically Driven Innovations in Aesthetic Surgery: Advances in Regenerative and Cellular Therapies

Regenerative and cellular therapies are transforming aesthetic surgery by using biologically driven methods to enhance tissue quality and clinical outcomes. This review highlights the effectiveness of adipose-derived stem cells (ADSCs) and stromal vascular fraction (SVF) in promoting angiogenesis, reducing inflammation, and remodeling the extracellular matrix, making them dominant in facial rejuvenation and scar treatment. Platelet-rich plasma (PRP) is beneficial for improving skin texture and healing, while non-adipose mesenchymal stem cells (MSCs) have limited use due to regulatory issues. Despite the promising results, challenges remain in standardizing preparation protocols and conducting long-term studies. Future advancements will rely on standardized techniques and new biotechnologies like exosomes, emphasizing natural outcomes and personalized care.