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Glossary Microneedle

Microneedles are tiny, minimally invasive needles that are used in various dermatological and cosmetic procedures, including hair restoration treatments. They create micro-injuries in the scalp, which can stimulate the body's natural healing processes and enhance the absorption of topical treatments, such as minoxidil. This technique is relevant to hair loss as it may promote hair growth by increasing blood flow and delivering therapeutic agents more effectively to hair follicles. Key distinguishing characteristics include their small size, typically ranging from 0.1 to 1.5 millimeters in length, and their ability to induce a controlled inflammatory response without causing significant pain or damage to the skin.

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learn Microneedling

Technique that makes tiny punctures in the scalp with fine needles

How does microneedling boost hair growth in thinning areas of the scalp? Small trials suggest microneedling may help mainly as an add-on to minoxidil; how it works in humans is not established, and the FDA has not cleared any microneedling device for hair loss.
Can microneedling make topical treatments like minoxidil work better? Small trials report more hair growth when microneedling is added to minoxidil, but the evidence is low quality, and the FDA has not cleared any microneedling device for hair loss or for use with minoxidil.
How often should microneedling be done for safe and effective results on hair loss? Studies have used intervals from weekly to monthly; no trial has compared intervals, and no microneedling device is FDA-cleared for hair loss.
All 4 questions on Microneedling →

learn Minoxidil

What microneedling is? Microneedling uses fine needles to make tiny skin wounds that trigger healing. Some devices are FDA-authorized for acne scars; none is authorized for hair loss, where evidence comes mainly from small studies.

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Research

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research Microneedles in the clinic

203 citations , May 2017 in “Journal of controlled release”

This review discusses completed and ongoing clinical studies on microneedle-based technologies for cosmetic, therapeutic, and diagnostic applications and reports no new clinical results.

research A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth

192 citations , April 2019 in “ACS nano”

In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.

research Microneedles as the technique of drug delivery enhancement in diverse organs and tissues

140 citations , December 2017 in “Journal of Controlled Release”

This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.

research Microneedle applications in improving skin appearance

131 citations , May 2015 in “Experimental Dermatology”

This review explores the development and cosmeceutical applications of microneedles for skin treatment, without reporting new clinical results, emphasizing safety and public perception as key factors for commercialization.

research Review of applications of microneedling in dermatology

108 citations , August 2017 in “Clinical, Cosmetic and Investigational Dermatology”

This review highlights microneedling's promise as an adjuvant therapy for enhanced drug delivery in dermatology, especially for conditions like atrophic scars and pigmentation disorders, though its efficacy for vitiligo is limited.

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Community Join

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community Where have all the microneedle pens gone?

in Microneedling 15 upvotes 1 year ago

Microneedle pens for hair loss are harder to find on Amazon due to FDA regulations on needle length. Users suggest buying from AliExpress or Temu instead.

community microneedle, any long term users damage?

in Microneedling 35 upvotes 2 years ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

community Microneedle and aloe vera after?

in Microneedling 5 upvotes 4 years ago

The user plans to use a 1.5 mm dermapen for microneedling every 10 days and is considering applying aloe vera afterward. They also inquire about the timing for washing their hair before and after the treatment.

community Losing Hair from Microneedling?

4 upvotes 2 weeks ago

Microneedling can cause hair shedding due to follicle puncturing, especially when using a 1mm depth. Users suggest using a dermastamp with a depth of 0.6-1mm and caution against home microneedling to avoid damaging hair follicles.

community How often should I microneedle. And what length?

2 upvotes 3 weeks ago

Microneedling for hair loss involves using 0.25-0.5mm needles multiple times a week for Minoxidil absorption and 1.0-1.5mm needles once every two weeks to a month for deep follicle stimulation. One user prefers using 1.5mm needles every two weeks, separate from Minoxidil application days.

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