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    Glossary Microneedle

    Microneedles are tiny, minimally invasive needles that are used in various dermatological and cosmetic procedures, including hair restoration treatments. They create micro-injuries in the scalp, which can stimulate the body's natural healing processes and enhance the absorption of topical treatments, such as minoxidil. This technique is relevant to hair loss as it may promote hair growth by increasing blood flow and delivering therapeutic agents more effectively to hair follicles. Key distinguishing characteristics include their small size, typically ranging from 0.1 to 1.5 millimeters in length, and their ability to induce a controlled inflammatory response without causing significant pain or damage to the skin.

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    1. Microneedles in the clinic Journal of controlled release · 2017 · 203 citations
    2. A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth ACS nano · 2019 · 192 citations
    3. Microneedles as the technique of drug delivery enhancement in diverse organs and tissues Journal of Controlled Release · 2017 · 140 citations
    4. Microneedle applications in improving skin appearance Experimental Dermatology · 2015 · 131 citations
    5. Review of applications of microneedling in dermatology Clinical, Cosmetic and Investigational Dermatology · 2017 · 108 citations
    6. Combined autologous platelet-rich plasma with microneedling verses microneedling with distilled water in the treatment of atrophic acne scars: a concurrent split-face study Journal of Cosmetic Dermatology · 2016 · 106 citations
    7. Microneedling: Where do we stand now? A systematic review of the literature Journal of Plastic Reconstructive and Aesthetic Surgery · 2017 · 92 citations
    8. Microneedles as transdermal drug delivery system for enhancing skin disease treatment Acta Pharmaceutica Sinica B · 2024 · 91 citations
    9. A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations and Applications Polymers · 2021 · 86 citations
    10. Design and fabrication of customizable microneedles enabled by 3D printing for biomedical applications Bioactive Materials · 2023 · 81 citations
    11. Application of microneedle patches for drug delivery; doorstep to novel therapies Journal of Tissue Engineering · 2022 · 76 citations
    12. Transcutaneous implantation of valproic acid-encapsulated dissolving microneedles induces hair regrowth Biomaterials · 2018 · 68 citations
    13. Response to microneedling treatment in men with androgenetic alopecia who failed to respond to conventional therapy Indian Journal of Dermatology · 2015 · 68 citations
    14. Advanced nanocarrier- and microneedle-based transdermal drug delivery strategies for skin diseases treatment Theranostics · 2022 · 67 citations
    15. Recent advances in microneedle composites for biomedical applications: Advanced drug delivery technologies Materials Science and Engineering: C · 2019 · 64 citations
    16. Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration Bioactive Materials · 2023 · 61 citations
    17. Dissolving microneedles: Applications and growing therapeutic potential Journal of Controlled Release · 2022 · 61 citations
    18. Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery Biomaterials Science · 2023 · 60 citations
    19. Repeated Microneedle Stimulation Induces Enhanced Hair Growth in a Murine Model Annals of Dermatology · 2016 · 55 citations
    20. Microneedles as Enhancer of Drug Absorption Through the Skin and Applications in Medicine and Cosmetology Journal of pharmacy & pharmaceutical sciences · 2018 · 55 citations
    21. Alopecia areata-successful outcome with microneedling and triamcinolone acetonide Journal of Cutaneous and Aesthetic Surgery · 2014 · 53 citations
    22. Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns Aesthetic Surgery Journal · 2016 · 49 citations
    23. Microneedle-Based Approaches for Skin Disease Treatment Nano-Micro Letters · 2025 · 48 citations
    24. Lamprey-Teeth-Inspired Oriented Antibacterial Sericin Microneedles for Infected Wound Healing Improvement Nano Letters · 2022 · 48 citations
    25. A comparative study of microneedling with platelet-rich plasma plus topical minoxidil (5%) and topical minoxidil (5%) alone in androgenetic alopecia International Journal of Trichology · 2017 · 48 citations
    26. Smart Microneedles for Therapy and Diagnosis Research · 2020 · 46 citations
    27. Microneedle Arrays Combined with Nanomedicine Approaches for Transdermal Delivery of Therapeutics Journal of Clinical Medicine · 2021 · 42 citations
    28. 3D Printing—A “Touch-Button” Approach to Manufacture Microneedles for Transdermal Drug Delivery Pharmaceutics · 2021 · 42 citations
    29. 3D printed microneedles: revamping transdermal drug delivery systems Drug Delivery and Translational Research · 2024 · 41 citations
    30. Microneedle Array Patch Made of Kangfuxin/Chitosan/Fucoidan Complex Enables Full-Thickness Wound Healing Frontiers in Chemistry · 2022 · 40 citations