Wound Healing, Cutaneous Therapy, Hair
November 2008
in “
Medical & surgical dermatology
”
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Studysummary This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles. Our plain-language summary of this paper — not a Tressless recommendation.
In 2008, a mechanical device was developed to measure the cross-sectional area of a hair bundle and scalp area, showing a correlation between hair bundle size and hair loss severity. The device's accuracy depended on careful sampling and was intended for uncut hair longer than 1 inch. Further clinical studies were needed to validate its effectiveness. Several studies on wound healing and hair growth were also conducted. Findings included the discovery that the frizzy mutation in mice is not an allele of Fgfr2, the transcription factor C/EBPx is a marker of preadipocytes in vivo, and Cyclosporin A induced fast telogen to anagen transition in mice. Research also found that combined inhibition of plasmin and metalloproteinases prevents healing, hyperbaric oxygen improves ischemic wound healing, and amniotic membranes have better wound-healing effects than polyurethane foam. Additionally, recombinant human vascular endothelial growth factor (rhVEGF165) released from a fibrin matrix increased tissue flap viability and induced VEGF-R2 expression, and basic fibroblast growth factor (bFGF) improved wound healing quality and reduced scarring in a rabbit ear model.
