Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by Increasing Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps

    November 2019 in “ Mediators of inflammation
    Chi Ming Pu, Ya Chun Chen, Yu Chen Chen, Tzu Lin Lee, Peng Yu, Shun Hua Chen, Yu Hsiu Yen, Chung‐Liang Chien, Jung‐Hsien Hsieh
    TLDR IL-6 from stem cells helps repair skin and grow hair.
    The study demonstrated that Interleukin-6 (IL-6) secreted by adipose-derived stem cells (ADSCs) significantly promoted tissue repair in ischemia/reperfusion-treated skin flaps by increasing cell proliferation and the formation of new hair follicles. The findings suggested that IL-6 played a crucial role in enhancing the regenerative capabilities of ADSCs, making them a promising therapeutic option for improving skin flap viability and promoting hair growth in damaged tissues.
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