Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by Increasing Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps

    November 2019 in “ Mediators of inflammation ”
    Chi Ming Pu, Ya Chun Chen, Yu Chen Chen … Jung‐Hsien Hsieh
    Studysummary This study found that adipose-derived stem cell-conditioned media improved skin flap survival following ischemia/reperfusion injury in mice by increasing cell proliferation and the number of hair follicles, mediated by IL-6.
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    Research cited in this study 6

    1. Regeneration of Dermis: Scarring and Cells Involved Cells · 2019
    2. Sericin Hydrogels Promote Skin Wound Healing with Effective Regeneration of Hair Follicles and Sebaceous Glands After Complete Loss of Epidermis and Dermis Biomaterials Science · 2018
    3. Hair Follicle Growth by Stromal Vascular Fraction-Enhanced Adipose Transplantation in Baldness Stem cells and cloning · 2017
    4. dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration Cell Stem Cell · 2015
    5. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015
    6. Hair Growth Stimulated by Conditioned Medium of Adipose-Derived Stem Cells Is Enhanced by Hypoxia: Evidence of Increased Growth Factor Secretion Biomedical research · 2010