Increased Expression of Zyxin and Its Potential Function in Androgenetic Alopecia

    January 2021 in “ Frontiers in Cell and Developmental Biology ”
    Qing-Mei Liu, Xiangguang Shi, Yue Zhang … Wenyu Wu
    Studysummary This study found that elevated expression of the protein Zyxin in hair follicles is associated with androgenetic alopecia and suggests it may be targeted for therapy.
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    Research cited in this study 16

    1. Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold Biomolecules · 2020
    2. Alpha-Parvin Is Required for Epidermal Morphogenesis, Hair Follicle Development, and Basal Keratinocyte Polarity PloS one · 2020
    3. A Combination of Pyridine-2, 4-Dicarboxylic Acid Diethyl Ester and Resveratrol Stabilizes Hypoxia-Inducible Factor 1-Alpha and Improves Hair Density in Female Volunteers International Journal of Cosmetic Science · 2020
    4. Androgenetic Alopecia: Combing the Hair Follicle Signaling Pathways for New Therapeutic Targets and More Effective Treatment Options Expert Opinion on Therapeutic Targets · 2019
    5. Insights into Male Androgenetic Alopecia: Differential Gene Expression Profiling of Plucked Hair Follicles and Integration with Genetic Data Journal of Investigative Dermatology · 2018
    6. Androgenetic Alopecia: A Review Endocrine · 2017
    7. Infundibular Protein and RNA Microarray Analyses from Affected and Clinically Non-Affected Scalp in Male Androgenetic Alopecia Patients Experimental Dermatology · 2017
    8. Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia Journal of Investigative Dermatology · 2016
    9. Proteomic Analysis of Balding and Non-Balding Mesenchyme-Derived Dermal Papilla Cells from Androgenetic Alopecia Patients Using Online Two-Dimensional Reversed Phase-Reversed Phase LC-MS/MS Journal of Proteomics · 2013
    10. Tenascin-C and Tenascin-W in Whisker Follicle Stem Cell Niches: Possible Roles in Regulating Stem Cell Proliferation and Migration Journal of Cell Science · 2013
    11. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    12. The Enhancement of Dermal Papilla Cell Aggregation by Extracellular Matrix Proteins Through Effects on Cell–Substratum Adhesivity and Cell Motility Biomaterials · 2009
    13. Androgenetic Alopecia: Clinical Features, Classification, and Treatments Endocrinology and Metabolism Clinics of North America · 2007
    14. Human Hair Growth Ex Vivo Is Correlated With In Vivo Hair Growth: Selective Categorization of Hair Follicles for More Reliable Hair Follicle Organ Culture Archives of Dermatological Research · 2005
    15. Androgenetic Alopecia in Men Aged 40-69 Years: Prevalence and Risk Factors British Journal of Dermatology · 2003
    16. Changing Patterns of Localization of Putative Stem Cells in Developing Human Hair Follicles Journal of Investigative Dermatology · 2000

    Related research 7

    1. An Extract of Leontopodium Alpinum Inhibits Catagen Development Ex Vivo and Increases Hair Density In Vivo International Journal of Cosmetic Science · 2022
    2. Increased Expression of Zyxin and Its Potential Function in Androgenetic Alopecia Frontiers in Cell and Developmental Biology · 2021
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