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    Glossary Keratinocyte Apoptosis

    process where skin cells undergo programmed cell death

    Keratinocyte apoptosis is the process by which keratinocytes, the primary cells in the outer layer of the skin, undergo programmed cell death. This is a natural and essential mechanism for maintaining skin health, as it helps remove damaged or unnecessary cells, allowing for the regeneration of new, healthy skin cells.

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    1. Indications for a brain‐hair follicle axis: inhibition of keratinocyte proliferation and up‐regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P The FASEB Journal · 2001 · 125 citations
    2. Activation of Cutaneous Protein Kinase Cα Induces Keratinocyte Apoptosis and Intraepidermal Inflammation by Independent Signaling Pathways The Journal of Immunology · 2003 · 74 citations
    3. Glycyrrhizic Acid Alleviates Osimertinib‐Induced Cutaneous Toxicity by Inhibiting Keratinocyte Apoptosis and Inflammation Phytotherapy Research · 2026
    4. Dihydrotestosterone Induces Keratinocyte Apoptosis by Activating ERK Signaling In Vivo · 2026
    5. Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism APOPTOSIS · 2011 · 52 citations
    6. Araliadiol Protects Human Keratinocytes From Oxidative Stress, DNA Damage, and Apoptosis via Activation of Antioxidant Signaling Frontiers in Bioscience-Landmark · 2026
    7. 15-deoxy prostaglandin J2, the nonenzymatic metabolite of prostaglandin D2, induces apoptosis in keratinocytes of human hair follicles: a possible explanation for prostaglandin D2-mediated inhibition of hair growth Naunyn-Schmiedeberg's Archives of Pharmacology · 2016 · 11 citations
    8. Vitamin D inhibits captopril-induced cell detachment and apoptosis in keratinocytes 2010 · 8 citations
    9. Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes Iranian journal of pharmaceutical research · 2025 · 1 citations
    10. Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes Journal of Investigative Dermatology · 2007 · 171 citations
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    Community 1 of 5

    1. Sugars ARE important for hair growth | Glycosaminoglycans as Hair Growth Stimulant Reddit · 30 Jul 2024
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