The Hair Loss Encyclopedia

Search

for
Search:

Glossaryp75 neurotrophin receptor (p75NTR)

protein on cell surfaces regulating survival and apoptosis

The p75 neurotrophin receptor (p75NTR) is a protein found on the surface of certain cells, including neurons and hair follicle cells. It plays a crucial role in regulating cell survival, growth, and apoptosis (programmed cell death) by binding to neurotrophins, which are a family of proteins that promote the survival and function of neurons. This receptor is significant in both the development of the nervous system and in conditions like alopecia, where it can influence hair follicle health and regeneration.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 93 results

Probing the Effects of Stress Mediators on the Human Hair Follicle

research Probing the Effects of Stress Mediators on the Human Hair Follicle

159 citations, December 2007 in “American Journal of Pathology”

Stress-related substance P may lead to hair loss and negatively affect hair growth.

research Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways

3 citations, July 2023 in “International journal of molecular sciences”

Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.

P75 Neurotrophin Receptor Antagonist Retards Apoptosis-Driven Hair Follicle Involution (Catagen)

research P75 Neurotrophin Receptor Antagonist Retards Apoptosis-Driven Hair Follicle Involution (Catagen)

24 citations, January 2003 in “Journal of Investigative Dermatology”

Blocking a specific receptor slows down hair loss in mice.

A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression

research A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression

96 citations, October 2000 in “The FASEB Journal”

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles

research New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles

12 citations, April 2020 in “British Journal of Dermatology”

Caffeine may help reduce stress-induced hair loss.

View more "p75ntr" in research →

Community Join

0 / 0 results

— no results