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    Glossary Neurotrophins

    proteins that support neuron growth, survival, and function

    Neurotrophins are a family of proteins that play a crucial role in the growth, survival, and maintenance of neurons, which are the cells responsible for transmitting information in the nervous system. They help support the health of nerve cells and are involved in processes like learning and memory. For professionals, key members of this family include nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF).

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    1. Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR. PubMed · 1998 · 122 citations
    2. Epithelial growth control by neurotrophins: leads and lessons from the hair follicle Progress in brain research · 2004 · 99 citations
    3. Overexpression of neurotrophin 4 in skin enhances myelinated sensory endings but does not influence sensory neuron number The Journal of Comparative Neurology · 2006 · 34 citations
    4. Neurotrophin-4 modulates the mechanotransducer Cav3.2 T-type calcium current in mice down-hair neurons Biochemical journal · 2011 · 11 citations
    5. Effects of Hura crepitans and Its Active Ingredient, Daphne Factor F3, on Dihydrotestosterone-Induced Neurotrophin-4 Activation and Hair Retardation Biological & Pharmaceutical Bulletin · 2012 · 5 citations
    6. The relationship between psychological distress and neurotrophins in patients with alopecia areata: A crosssectional study TURKDERM · 2025
    7. Neurotrophins, nociceptors, and pain Microscopy Research and Technique · 1999 · 189 citations
    8. A role for p75 neurotrophin receptor in the control of apoptosis‐driven hair follicle regression The FASEB Journal · 2000 · 96 citations
    9. p75 Neurotrophin Receptor Antagonist Retards Apoptosis-driven Hair Follicle Involution (Catagen) Journal of Investigative Dermatology · 2003 · 24 citations
    10. Retardation of Hair Follicle Development by the Deletion of TrkC, High-Affinity Neurotrophin-3 Receptor Journal of Investigative Dermatology · 1999 · 14 citations
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    1. Possible topical option for preventing BDNF-related hair loss Reddit · 23 Oct 2023

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