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GlossaryNeurotrophins

proteins that support neuron growth, survival, and function

Neurotrophins are a family of proteins that play a crucial role in the growth, survival, and maintenance of neurons, which are the cells responsible for transmitting information in the nervous system. They help support the health of nerve cells and are involved in processes like learning and memory. For professionals, key members of this family include nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF).

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research Neurotrophin-4 Modulates the Mechanotransducer Cav3.2 T-Type Calcium Current in Mice Down-Hair Neurons

11 citations, December 2011 in “Biochemical journal”

Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.

Effects of Hura Crepitans and Its Active Ingredient, Daphne Factor F3, on Dihydrotestosterone-Induced Neurotrophin-4 Activation and Hair Retardation

research Effects of Hura Crepitans and Its Active Ingredient, Daphne Factor F3, on Dihydrotestosterone-Induced Neurotrophin-4 Activation and Hair Retardation

5 citations, January 2012 in “Biological & Pharmaceutical Bulletin”

Hura crepitans and its compound daphne factor F3 may help treat hair loss by blocking a specific hair growth inhibitor.

research Inhibitory Effects of Polyacetylene Compounds from Panax Ginseng on Neurotrophin Receptor-Mediated Hair Growth

7 citations, January 2017 in “Biological & Pharmaceutical Bulletin”

Certain compounds from Panax ginseng can block proteins that affect hair growth, potentially helping treat hair loss.

research Epithelial Growth Control by Neurotrophins: Leads and Lessons from the Hair Follicle

99 citations, January 2004 in “Progress in brain research”

Neurotrophins are important for hair growth and could help treat hair loss.

research P75 Neurotrophin Receptor Antagonist Retards Apoptosis-Driven Hair Follicle Involution (Catagen)

24 citations, January 2003 in “Journal of Investigative Dermatology”

Blocking a specific receptor slows down hair loss in mice.

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community Possible topical option for preventing BDNF-related hair loss

in Research/Science 7 upvotes 11 months ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.