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Glossary Organogenesis

process where embryonic cells develop into organs and tissues

Organogenesis is the process during embryonic development where the three primary germ layers (ectoderm, mesoderm, and endoderm) differentiate and develop into the internal organs and tissues of an organism. This complex process involves cell signaling, gene expression, and tissue interactions to form structures like the heart, lungs, and liver, ensuring the proper function and organization of the body.

Research

5 / 941 results

research Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells

205 citations , April 2005 in “Journal of Investigative Dermatology”

This study describes a system for generating hair follicles from dissociated cells in mice, suggesting that successful development requires a foundational epithelial platform.

research Wnt signaling in skin organogenesis

72 citations , April 2008 in “Organogenesis”

This review discusses the roles of Wnt signaling in skin organogenesis and related processes but reports no new experimental results, highlighting areas for future research.

research Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis

4 citations , July 2022 in “Frontiers in Cell and Developmental Biology”

This review discusses the formation and maintenance of hair follicles through dynamic cellular changes and signaling pathways, presenting a comprehensive overview but providing no new experimental findings.

research Deconvolving organogenesis in space and time via spatial transcriptomics in thick tissues

3 citations , September 2024

This study developed 3DEEP, a tissue clearing and spatial transcriptomic method, to map hair follicle development in a single time point from a 12-hour-old mouse, detailing molecular stages, signaling dynamics, and structural changes within developing follicles.

research Developmental and reproductive outcome of F1 generation of Wistar rats exposed to Acanthus montanus aqueous extract during organogenesis

July 2008 in “Planta Medica”

This study found that Acanthus montanus leaves' aqueous extract is a developmental toxicant in rats, leading to several adverse effects on offspring when used during pregnancy.

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