Effect of PRP on the Proliferation of Dermal Papilla Cells and Hair Follicle Regeneration in Mice

March 2013 in “ PubMed ”

Yong Miao, Chuanbo Feng, Zhidan Zhang, Zehua Li, Shune Xiao, Jin-Dou Jiang, Zhiqi Hu

platelet-rich plasma PRP dermal papilla cells DPCs hair follicle regeneration MTT assay hair follicle density

TLDR PRP speeds up hair growth and increases hair follicle density in mice.

The study investigated the effects of platelet-rich plasma (PRP) on dermal papilla cells (DPCs) and hair follicle regeneration in mice. PRP was prepared and applied to DPCs, and its proliferative effect was measured using MTT assay. The study found that activated PRP significantly increased the proliferation and aggregative growth of DPCs. In the reconstituted skin area, 10% PRP resulted in a higher yield of hair follicles (344 +/- 27) compared to 0% PRP (288 +/- 35), with a 19.4% increase in hair follicle density. Additionally, 10% PRP shortened the time of hair formation to 18 +/- 1 days compared to 20 +/- 1 days with 0% PRP. The study concluded that PRP had a considerable effect on both the time of hair formation and the yield of hair follicle reconstitution.

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in Female 7 upvotes 3 years ago

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community PRP ( PLATELET-RICH-PlASMA) for hair loss

in Treatment 1 upvotes 1 year ago

A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

community 8 years of Finasteride and Minoxidil (includes a photo)

in Update 71 upvotes 1 year ago

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community Oral Fin/Min 6 month before and after

in Progress Pictures 100 upvotes 1 year ago

A user experienced significant hair regrowth after 6 months using 1mg Finasteride and Oral Minoxidil, along with pumpkin seed oil, biotin, and collagen supplements, and is considering starting PRP. Another user has not seen results despite using a combination of treatments including finasteride, minoxidil, RU58841, pyrithione zinc, topical dutasteride, ketoconazole, and microneedling.

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