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    GlossaryMTT assay

    measures cell viability by converting yellow dye to purple

    The MTT assay, also known as the MTT reduction assay, is a laboratory test used to measure cell viability and proliferation. It involves adding a yellow dye called MTT to cells; living cells convert this dye into a purple formazan product, which can be quantified by measuring its absorbance with a spectrophotometer. This assay is commonly used in research to assess the effects of drugs, toxins, or other treatments on cell health.

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      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 3 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community TDM-105795 phase 2 results are in!

      in Research/Science  31 upvotes 2 years ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community GT20029. Kintor Pharma’s Product

      in Research/Science  13 upvotes 3 years ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.