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    Glossary TUNEL assay

    detects DNA fragmentation in cells undergoing apoptosis

    The TUNEL assay, or Terminal deoxynucleotidyl transferase dUTP nick end labeling, is a laboratory technique used to detect DNA fragmentation resulting from apoptotic signaling. It works by labeling the ends of broken DNA strands, allowing researchers to identify and quantify cells undergoing programmed cell death, which can be important in studies of diseases like cancer or conditions affecting hair follicles, such as alopecia.

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    1. Detection of Bim and Puma in mouse hair follicles using immunofluorescence and TUNEL assay double staining Biotechnic & histochemistry · 2015 · 3 citations
    2. YAP and TAZ are essential for basal and squamous cell carcinoma initiation EMBO Reports · 2018 · 76 citations
    3. A primer for studying cell cycle dynamics of the human hair follicle Experimental Dermatology · 2016 · 38 citations
    4. Apoptotic cell death in canine hair follicle. PubMed · 2005 · 5 citations
    5. Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture Experimental Dermatology · 2009 · 132 citations
    6. Therapeutic small extracellular vesicles from key human stem and immune cellular sources: A review Journal of Biomedical Research · 2026
    7. The patch assay reconstitutes mature hair follicles by culture-expanded human cells Regenerative Medicine · 2017 · 11 citations
    8. Undifferentiated connective tissue disease presenting with vascular pattern of renal amyloidosis with carpel tunnel syndrome: A case report International Journal of Case Reports and Images · 2014
    9. “Two-Cell Assemblage” Assay: A Simple in vitro Method for Screening Hair Growth-Promoting Compounds Frontiers in Cell and Developmental Biology · 2020 · 5 citations
    10. Improving selective androgen receptor modulator discovery and preclinical evaluation Expert Opinion on Drug Discovery · 2009 · 11 citations
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