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GlossaryTUNEL assay

detects DNA fragmentation in cells undergoing apoptosis

The TUNEL assay, or Terminal deoxynucleotidyl transferase dUTP nick end labeling, is a laboratory technique used to detect DNA fragmentation resulting from apoptotic signaling. It works by labeling the ends of broken DNA strands, allowing researchers to identify and quantify cells undergoing programmed cell death, which can be important in studies of diseases like cancer or conditions affecting hair follicles, such as alopecia.

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community 9 months fin+microneedling/2 years min, looks like there’s a light at the end of the tunnel

in Progress Pictures 100 upvotes 1 year ago

User shared 9-month progress with finasteride and microneedling, and 2-year progress with minoxidil for hair loss. Others asked about microneedling tools, routine, and suggested micro fibers for improvement.

community Exosome Hair Rejuvenation (2nd Month UPDATE!)

in Progress Pictures 3 upvotes 1 year ago

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

community Why balding gets worse in every generation?

in Chat 81 upvotes 1 month ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community More great news about SCUBE3… this could be it!

in Research/Science 30 upvotes 1 year ago

SCUBE3 is a potential hair loss treatment that people are hopeful about. It may provide a solution without the side effects of finasteride.

community My Hairline journey. The first photo taken is the day I took the pill. No date specific just know I’ve been on finasteride 22 months. 2 years November 14th. ASK ANYTHING. Oh yeah started minoxidil a year later. Once every day or every other day super inconsistent and never really use 1ml, maybe half

in Progress Pictures 1 year ago

. Fin from Inhouse This user has been taking finasteride for 22 months and minoxidil for 1 year to reduce hair loss, with apparent success; they have also avoided tight cornrow hairstyles to further protect their hairline.

community Meta analysis: Topical or mesotherapy dutasteride is more effective than topical finasteride in the treatment of AGA in men

in Research/Science 19 upvotes 2 years ago

Topical Dutasteride is more effective than topical Finasteride for treating AGA in men, with fewer side effects. Mesotherapy with Dutasteride, administered every 3 months, shows promising results for hair regrowth and maintenance without daily routines or significant side effects.

community I just want to say hello to all my fellow Dutasteride Master Racers!

in Satire 64 upvotes 1 month ago

The conversation humorously discusses hair loss treatments, specifically Dutasteride. Users share experiences and joke about the high cost and effectiveness of the treatment.

community r/Tressless bros in a nutshell

in Satire 632 upvotes 4 months ago

The conversation discusses personal experiences with hair loss treatments, specifically Minoxidil and Finasteride, with some users regretting not starting treatment earlier and others experiencing side effects. Some users are considering or have switched to topical formulations due to side effects from oral medications.

community Shedding on finasteride only; looking for motivation

in Finasteride/Dutasteride 14 upvotes 5 months ago

A user started finasteride for hair loss and saw improvement, but is now experiencing shedding and thinning in new areas. They added Nizoral due to dandruff caused by finasteride. Replies suggest that shedding is normal around 6 months and advise to stick with the treatment.

community TresslessGPT is available to ChatGPT Plus users

in 📣 Announcement 104 upvotes 7 months ago

The conversation introduces a specialized chatbot for ChatGPT Plus users that provides advice on hair loss treatments, drawing from research and community insights. It mentions treatments like RU58841, the "big 4" (likely minoxidil, finasteride, ketoconazole, and tretinoin), dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

community Dutasteride 1 year regression. Depressing. (With pictures for proof)

in Progress Pictures 14 upvotes 8 months ago

A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.

community About Verteporfin but not about hair

in Technology 17 upvotes 9 months ago

Verteporfin treatment shows promise for hair regeneration and reducing scar tissue in hair transplants. Some users plan to try verteporfin with hair transplants, and it may also be combined with PRP in future experiments.

community What 9 months of daily oral Fin/Min (1mg/2.5mg) progress looks like.

in Progress Pictures 137 upvotes 9 months ago

A user's 9-month progress using daily oral Fin/Min (1mg/2.5mg) for hair loss. The user experienced prolonged shedding but saw significant improvement by month 6, and took the medication in pill form as prescribed by their doctor.

community There is news from pyrilutamide?

in Product 32 upvotes 10 months ago

The discussion is about a hair loss drug called pyrilutamide. Users discuss its efficacy, safety, and expected market release around 2025-2026, with some expressing concerns about the authenticity of current market offerings.

community In Mozambique you need to take finasteride to save your life

in Satire 509 upvotes 1 year ago

The conversation is about hair loss and the specific treatments mentioned are finasteride and minoxidil.

community Have you noticed any difference in mood or energy since being on fin/dut?

in Finasteride/Dutasteride 25 upvotes 1 year ago

Users discuss effects of Finasteride/Dutasteride on mood and energy. Some experience depression, focus issues, and libido changes.

community 2 years of Dutasteride. Not sure if I had proper MPB, or TE following drastic weight loss. But here it is (5 pics from then, and 6 from now).

in Progress Pictures 33 upvotes 1 year ago

User experienced hair thinning after losing 100 lbs and started Dutasteride treatment. They faced side effects like fatigue, brain fog, and insomnia but no erectile dysfunction.

community Pyrilutamide – anybody getting real gains from it?

in Finasteride/Dutasteride 29 upvotes 1 year ago

People's experiences with Pyrilutamide as a hair loss treatment, including anecdotal evidence of regrowth and reduced scalp itch when used in conjunction with Finasteride and Minoxidil.

community It took 8 months on finasteride before I saw any progress. Progress pictures, advice, and my routine are listed below.

in Progress Pictures 40 upvotes 3 years ago

A user shared their hair loss journey, seeing significant improvement after 8 months using finasteride, minoxidil, dermarolling, and supplements. They went from NW 3 to NW 1.5 and emphasized better sleep.

community Wasn't Breezula supposed to post some results soon?

in Question 17 upvotes 5 years ago

The conversation is about expecting results from Breezula, a hair loss treatment, with no new information released as of April 1st. Some joked it's just onion juice, while another comment suggested a conspiracy to cause baldness.

community SHISEIDO is A Bust...

in Update 25 upvotes 5 years ago

Shiseido's hair loss treatment reported only 5% regrowth, disappointing many. Users discussed other treatments like Minoxidil, finasteride, RU58841, and CB-03-01 as potential alternatives.

community I am not losing my hair (yet) and do not think I will soon, but I am a pre medicine major who has an obsession over stem cells and want to share something with you all. Your future is brighter than you think.

19 upvotes 6 years ago

User hoodoomoovoo discusses their interest in stem cell research and its potential for hair loss treatment. They share links to studies and mention ongoing trials, expressing optimism for a future solution to hair loss.

community lost my hair in a single year of treatment at 20 years old

in Finasteride/Dutasteride 87 upvotes 3 weeks ago

A 20-year-old lost significant hair after one year of treatment, using minoxidil, finasteride, and later dutasteride. They are considering adding RU58841 but are advised to return to finasteride and minoxidil for a year before deciding.

community Life after minoxidil? Has anyone stopped

in Update 147 upvotes 2 months ago

A user stopped using minoxidil after 10-12 years due to severe side effects like fluctuating blood pressure and chest pain, resulting in significant hair loss. Other users shared similar experiences, emphasizing health over hair and suggesting alternatives like finasteride, nanoxidil, and rosemary oil.

community Are most men bald because they haven’t tried any treatment or are they bald in spite of it?

in Shaved/buzzed 307 upvotes 4 months ago

Some men are bald because they are unaware of hair loss treatments like Minoxidil (Min) and Finasteride (Fin), while others choose not to use them due to potential side effects, cost, or personal preference. Treatments like Min and Fin are discussed, with varying results and opinions on their effectiveness and side effects.

community Post Finasteride Syndrome, A dangerous lie.

in Chat 142 upvotes 5 months ago

A user initially had side effects from finasteride, attributed them to anxiety and the nocebo effect, and after resuming the drug, experienced positive effects and now warns against misinformation about Post Finasteride Syndrome.

community 19 yo destroyed hairline even though using Fin/min/microneedling for 16months/11months/3months … Idk what to do.

in Progress Pictures 260 upvotes 7 months ago

A 19-year-old has been using finasteride, minoxidil, and microneedling to treat hair loss with no regrowth, feeling mentally affected by it. Advice given includes continuing treatment, considering a hair transplant, addressing potential vitamin deficiencies, and possibly switching to dutasteride or adding ketoconazole shampoo.

community Finasteride vs Dutasteride: The Science

in Research/Science 168 upvotes 7 months ago

The conversation compares Finasteride and Dutasteride for hair loss treatment, discussing their effectiveness and side effects. Users share personal results and consider combining treatments like Dutasteride with RU58841.

community 11 months on fin only. Regrowth + thickness

in Progress Pictures 571 upvotes 7 months ago

A user reported hair regrowth and increased thickness after 11 months using finasteride 1mg, taken 3-4 times a week, with noticeable improvement starting around the third or fourth month. No side effects were mentioned, and the user is considering reducing the dosage to find the minimum needed to maintain results.

community It’s getting worse. (4 months)

in Update 203 upvotes 7 months ago

The conversation discusses hair loss treatments, with users suggesting the use of finasteride daily, considering minoxidil for aggressive hair loss, and discussing the normalcy of shedding during treatment. Some users recommend adding Nizoral shampoo and switching to dutasteride for better results.