Lenalidomide Augments Differentiation of Cultured Hair Follicle Derived Melanocyte Stem Cells Into Functional Melanocytes

    April 2023 in “ Dermatology practical & conceptual ”
    Uma Kumari, Naveed Pervaiz, Harjot Kaur … Rajneesh Kumar
    Studysummary This study concluded that lenalidomide significantly induces the proliferation and migration of melanocyte stem cells, enhancing their differentiation into functional melanocytes in a mouse model.
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    Research cited in this study 7

    1. CD34 Defines Melanocyte Stem Cell Subpopulations With Distinct Regenerative Properties PLOS genetics · 2019
    2. The Human Hair: From Anatomy to Physiology International Journal of Dermatology · 2013
    3. Hair Repigmentation Associated with the Use of Lenalidomide: Graying May Not Be an Irreversible Process Journal of oncology pharmacy practice · 2012
    4. Melanocyte Stem Cells: A Melanocyte Reservoir in Hair Follicles for Hair and Skin Pigmentation Pigment Cell & Melanoma Research · 2011
    5. Human Dermal Stem Cells Differentiate Into Functional Epidermal Melanocytes Journal of Cell Science · 2010
    6. Nascent Blood Vessels in the Skin Arise from Nestin-Expressing Hair-Follicle Cells Proceedings of the National Academy of Sciences · 2004
    7. Nestin Expression in Hair Follicle Sheath Progenitor Cells Proceedings of the National Academy of Sciences · 2003

    Related research 3

    1. Lenalidomide Augments Differentiation of Cultured Hair Follicle Derived Melanocyte Stem Cells Into Functional Melanocytes Dermatology practical & conceptual · 2023
    2. Regulation of Melanocyte Stem Cells in the Pigmentation of Skin and Its Appendages: Biological Patterning and Therapeutic Potentials Experimental Dermatology · 2018
    3. Stem Cells of the Hair Follicular Tissue: Application in Cell-Based Therapy for Vitiligo Hair therapy & transplantation · 2015