Biochemical and Histopathological Evaluation of the Radioprotective Effects of Melatonin Against Gamma Ray-Induced Skin Damage

    November 2018 in “ Current radiopharmaceuticals ”
    Dheyauldeen Shabeeb, Masoud Najafi, Ahmed Eleojo Musa … Hedayat Samandari
    Studysummary This study found that melatonin, when administered to Wistar rats prior to and after radiation exposure, reduced oxidative stress markers and histopathological damage in skin tissue compared to radiation alone, suggesting it may effectively prevent and treat radiation-induced skin injury.
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    Research cited in this study 2

    1. Melatonin in the Skin: Synthesis, Metabolism, and Functions Trends in Endocrinology and Metabolism · 2008
    2. Caffeine Ameliorates Radiation-Induced Skin Reactions in Mice but Does Not Influence Tumor Radiation Response Journal of Radiological Protection · 2002