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Glossary Free Radicals

unstable molecules with unpaired electrons causing cellular damage

Free radicals are unstable molecules that have an unpaired electron, making them highly reactive. They can cause damage to cells, proteins, and DNA by stealing electrons from other molecules, a process known as oxidative stress. This damage is linked to aging and various diseases, including cancer and neurodegenerative disorders.

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Research

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research Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair

160 citations , July 2008 in “Experimental dermatology”

This review discusses the protective effects and mechanisms of melatonin in skin and suggests potential therapeutic applications in cutaneous medicine, reporting no new clinical findings.

research Protective Effects of Zizyphus jujuba and Fermented Zizyphus jujuba from Free Radicals and Hair Loss

9 citations , August 2014 in “Journal of The Korean Society of Food Science and Nutrition”

This study found that Zizyphus jujuba, especially when fermented with Saccharomyces cerevisiae, showed strong antioxidative activity and effectively promoted hair regrowth and prevented hair loss in a mouse model.

A Fast and Simple FIA-Chemiluminescence Method for the Evaluation of Roselle Flowers as Scavengers of Free Radicals Generated by UV-Irradiated Antibiotics

research A fast and simple FIA-chemiluminescence method for the evaluation of Roselle flowers as scavenger of the free radicals generated by UV irradiated antibiotics

4 citations , November 2018 in “Journal of Pharmaceutical and Biomedical Analysis”

This study found that a hydro-alcoholic extract of Roselle petals may reduce free radical production during UV-induced photodecomposition of antibiotics, potentially offering protective benefits for patients using similar topical antibiotics.

research Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage

210 citations , May 2006 in “The FASEB journal”

This study found that oxidative stress in hair follicle melanocytes contributes to premature aging and apoptosis, providing insights into graying as a model for studying aging and testing antiaging therapies.

research EFFECT OF GELATIN-CYSTINE AND SERENOA REPENS EXTRACT ON FREE RADICALS LEVEL AND HAIR GROWTH

6 citations , January 1998 in “Journal of applied cosmetology”

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Community Join

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community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

484 upvotes 2 years ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community What Are the Technicalities of Curved Hair Transplantation?

4 upvotes 5 months ago

Curved hair transplantation requires specialized tools and techniques to avoid damaging hair follicles, with modified FUE being the preferred method. Proper extraction and implantation angles are crucial to prevent complications like keloids and sterile folliculitis.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community I had claude create a protocol only using fda approved drugs.

4 upvotes 8 months ago

A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

community Let Me Sell You on NAC

17 upvotes 7 years ago

The conversation discusses using NAC (N-Acetyl Cysteine) alongside minoxidil and finasteride for hair loss, with some users noting potential hairline improvement and increased energy. The original poster reduced their finasteride dosage due to mental decline and anxiety, and while NAC's effects on hair are anecdotal, it is considered low-risk with other health benefits.

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