Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports

February 2023 in “ International Journal of Molecular Sciences ”

Iva Bešlić, Liborija Lugović-Mihić, Alen Vrtarić, Ante Bešlić, Ivana Škrinjar, Milena Hanžek, Danijel Crnković, Marinko Artuković

melatonin androgenic alopecia telogen effluvium atopic dermatitis hyperpigmentation disorders scalp disorders photoprotection skin aging prevention skin regeneration

Studysummary This review discusses various therapeutic roles of melatonin, particularly its antioxidant and sleep-regulating properties, for skin and scalp conditions, and reports no new clinical results.

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research Natural Products for Male Androgenetic Alopecia

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Natural products like saw palmetto, caffeine, melatonin, marine extracts, rosemary oil, procyanidin, pumpkin seed oil, and cannabidiol oil could potentially treat male hair loss.

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research Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in Alzheimer's Disease and Rosacea

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This research reported that melatonin may serve as a potential treatment for both rosacea and Alzheimer's disease by regulating inflammation and vascular signaling pathways, demonstrating effectiveness in reducing symptoms associated with rosacea-like skin lesions in experimental settings.

research Protective Effects of Melatonin on the Skin: Future Perspectives

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This article reviews various studies and suggests that melatonin, produced both naturally in the skin and applied topically, may offer significant protection against environmental damage, making it a promising candidate for skincare therapies.

research Melatonin: A Cutaneous Perspective on Its Production, Metabolism, and Functions

185 citations , February 2018 in “Journal of Investigative Dermatology”

This review discusses melatonin's potential in dermatology, highlighting its antioxidative, immunomodulatory, and DNA repair properties, but reports no new clinical results.

research Stem Cell and Extracellular Matrix-Related Molecules Increase Following Melatonin Treatment in the Skin of Postmenopausal Rats

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This study found that melatonin treatment increased epidermal thickness, subcutaneous fat, and dermal-related factors in postmenopausal rats, suggesting benefits for skin structure after menopause.