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GlossaryPigmentation Disorders

conditions affecting skin, hair, or eye color due to melanin abnormalities

Pigmentation disorders are conditions that affect the color of your skin, hair, or eyes due to abnormal melanin production. These disorders can result in patches of skin that are lighter (hypopigmentation) or darker (hyperpigmentation) than the surrounding areas, and can be caused by genetic factors, sun exposure, or underlying health issues.

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research Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports

1 citations , February 2023 in “International Journal of Molecular Sciences”

Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.

research An Approach to Disorders of Pigmentation

September 2012 in “British Small Animal Veterinary Association eBooks”

The document concludes that pigmentation disorders in animals involve complex interactions between melanocytes and keratinocytes.

research Decrypting the Potential of Nanotechnology-Based Approaches as Cutting-Edge for Management of Hyperpigmentation Disorder

26 citations , December 2022 in “Molecules”

Nanotechnology can improve treatments for skin discoloration.

research Finasteride Inhibits Melanogenesis Through Regulation of the Adenylate Cyclase in Melanocytes and Melanoma Cells

11 citations , February 2018 in “Archives of Pharmacal Research”

Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.

research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis

January 2015

Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.

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community Can tretinoin cause problems or issues with min?

in Minoxidil 2 upvotes 8 months ago

The user is using a topical routine of finasteride and minoxidil, noticing increased hair growth, and is considering adding tretinoin for skin issues. Tretinoin may enhance minoxidil's effectiveness, but care should be taken to allow proper absorption to avoid unintended facial hair growth.

community Massive preliminary success with my thorough regime

in Update 4 upvotes 5 years ago

A 28-year-old male reported significant hair regrowth after 5 weeks using a regime including Minoxidil, Ketozolin shampoo, microneedling, hyaluronic acid, saw palmetto, pumpkin seed, MSM, frankincense, zinc, multivitamins, and vitamin D. He also noted improvements in digestion, dry eyes, and skin health, and observed beard growth from microneedling.

community Tretinoin vs. micro-needling: what increases sulfotransferase activity more?

in Research/Science 1 upvotes 5 months ago

Tretinoin and microneedling both enhance hair growth through different mechanisms, with microneedling being considered safe for long-term use. Optimal microneedling needle length varies, but 0.8 mm is suggested for hair growth, and a Dermastamp is recommended to avoid skin damage.

community Does finasteride/dutasteride reverse aging?

in Chat 45 upvotes 1 year ago

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

community Started Finasteride almost three months ago and I'm upset

in Update 153 upvotes 1 year ago

A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

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