Potential Involvement of the Stem Cell Factor Receptor c-kit in Alopecia Areata and Androgenetic Alopecia: Histopathological, Immunohistochemical, and Semiquantitative Investigations

    January 2010 in “ Acta Histochemica Et Cytochemica ”
    Md. Ashrafuzzaman, Tomoko Yamamoto, Noriyuki Shibata … Makio Kobayashi
    Studysummary This study found that patients with alopecia areata and androgenetic alopecia showed increased c-kit expression and decreased Ki-67 expression in hair follicle cells compared to controls, suggesting a possible feedback mechanism involving stem cell factor signaling.
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    Research cited in this study 5

    1. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    2. Stem Cell Factor/c-Kit Signaling in Normal and Androgenetic Alopecia Hair Follicles Journal of Endocrinology · 2008
    3. Stem Cells and Their Niches Science · 2006
    4. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    5. Potential Factors Contributing to Androgenetic Alopecia Springer eBooks · 1996

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    3. Potential Involvement of the Stem Cell Factor Receptor c-kit in Alopecia Areata and Androgenetic Alopecia: Histopathological, Immunohistochemical, and Semiquantitative Investigations Acta Histochemica Et Cytochemica · 2010
    4. Diseases of the Hair and Scalp Archives of Dermatology · 1994