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GlossaryNon-Lesional Control (NLC)

sample from unaffected area used for comparison in studies

Non-Lesional Control (NLC) refers to a sample of tissue or skin that is taken from an area not affected by a disease or condition, used as a baseline or comparison in scientific studies. In the context of hair and alopecia research, NLC samples are often compared to lesional samples (affected areas) to understand the differences and underlying mechanisms of the condition.

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research Formulation and Physicochemical Characterization of a Nanostructured Lipid Carrier Gel Combining Minoxidil and Finasteride for the Treatment of Alopecia in Prospective Hajj Pilgrims

April 2025 in “Jurnal Sains dan Teknologi Farmasi Indonesia”

The NLC gel with Minoxidil and Finasteride effectively treats hair loss in harsh conditions.

Optimization of Nanostructured Lipid Carriers for Crude Fucoidan Extract from Brown Algae (Sargassum Chrysanthemum): Design and Characterization

research Optimization of Nanostructured Lipid Carriers for Crude Fucoidan Extract from Brown Algae (Sargassum Chrysanthemum): Design and Characterization

December 2024 in “Tropical Journal of Natural Product Research”

The developed carrier may improve hair growth treatments using brown algae extract.

research Novel Natural Lipids Based NLC Containing Finasteride Improved Androgenetic Alopecia Treatment in Rats

October 2024 in “International Journal of Pharmaceutics”

Finasteride in lipid carriers improved hair growth in rats.

Nanostructured Lipid Carriers Composed of Argan Oil: A Potential Novel Vehicle for Caffeine Delivery to Stratum Corneum and Hair Follicles

research Nanostructured Lipid Carriers Composed of Argan Oil: A Potential Novel Vehicle for Caffeine Delivery to Stratum Corneum and Hair Follicles

January 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Argan oil-based nano carriers could potentially deliver caffeine to hair follicles to treat hair loss.

research Preparation and Characterization of Minoxidil Loaded Nanostructured Lipid Carrier Gel for Effective Treatment of Alopecia

101 citations, October 2013 in “Journal of The Saudi Pharmaceutical Society”

Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.

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community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 2 years ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Convinced dad to get into minox 2 months ago and fin 1 month ago

in Is this regrowth? 208 upvotes 1 year ago

A user convinced their dad to start using Minoxidil two months ago and Finasteride one month ago for hair regrowth. The dad is showing significant progress, and there are suggestions to add derma stamping for better results.

community Melatonin a possible tool to help fight AGA hair loss.

in Research/Science 46 upvotes 4 years ago

Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.