New Ethanol and Propylene Glycol Free Gel Formulations Containing a Minoxidil-Methyl-Beta-Cyclodextrin Complex as Promising Tools for Alopecia Treatment

    March 2014 in “ Drug Development and Industrial Pharmacy ”
    Nicola Margiotta, Annalisa Cutrignelli, Andreas Bernkop-Schnürch … Massimo Franco
    Studysummary This study evaluated new aqueous gel formulations of minoxidil without irritants and found that the calcium alginate gel showed the best performance in terms of drug release and skin permeation.
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    Research cited in this study 12

    1. Transcutol-Containing Vesicles for Topical Delivery of Minoxidil Journal of Drug Targeting · 2010
    2. The Effects of Particle Properties on Nanoparticle Drug Retention and Release in Dynamic Minoxidil Foams International Journal of Pharmaceutics · 2010
    3. Penetration Enhancer-Containing Vesicles as Carriers for Cutaneous Delivery of Minoxidil International Journal of Pharmaceutics · 2009
    4. Formulation and In Vitro Assessment of Minoxidil Niosomes for Enhanced Skin Delivery International Journal of Pharmaceutics · 2009
    5. Synthesis and Characterization of Inclusion Complex of the Vasodilator Drug Minoxidil with β-Cyclodextrin Journal of Inclusion Phenomena and Macrocyclic Chemistry · 2008
    6. Liposomes And Niosomes As Potential Carriers For Dermal Delivery Of Minoxidil Journal of Drug Targeting · 2007
    7. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    8. Minoxidil-Containing Dosage Forms: Skin Retention and After-Rinsing Hair-Growth Promotion Drug Delivery · 2003
    9. Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment Journal of The American Academy of Dermatology · 2002
    10. Penetration of Minoxidil from Ethanol/Propylene Glycol Solutions: Effect of Application Volume and Occlusion Journal of Pharmaceutical Sciences · 1995
    11. Relative Influence of Ethanol and Propylene Glycol Cosolvents on Deposition of Minoxidil into the Skin Journal of Pharmaceutical Sciences · 1994
    12. Topically Applied Minoxidil in Baldness International Journal of Dermatology · 1985

    Related research 1

    1. New Ethanol and Propylene Glycol Free Gel Formulations Containing a Minoxidil-Methyl-Beta-Cyclodextrin Complex as Promising Tools for Alopecia Treatment Drug Development and Industrial Pharmacy · 2014