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Research

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research Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream

34 citations , October 2014 in “European journal of pharmaceutics and biopharmaceutics”

This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.

research Gradient-dependent release of the model drug TRITC-dextran from FITC-labeled BSA hydrogel nanocarriers in the hair follicles of porcine ear skin

18 citations , October 2016 in “European Journal of Pharmaceutics and Biopharmaceutics”

In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.

research Triggered release of model drug from AuNP-doped BSA nanocarriers in hair follicles using IRA radiation

29 citations , November 2015 in “Acta Biomaterialia”

This study found that water-filtered infrared A radiation can induce the release of a model drug from gold nanoparticle-doped particles in hair follicles in an ex vivo porcine skin model, suggesting feasibility for follicular drug delivery systems.

research Triggering of drug release of particles in hair follicles

39 citations , April 2012 in “Journal of controlled release”

This study found that using a protease-triggered release system enabled effective delivery of a model drug deep within porcine hair follicles, suggesting a new approach for treating skin conditions.

research The effects of particle properties on nanoparticle drug retention and release in dynamic minoxidil foams

25 citations , January 2010 in “International Journal of Pharmaceutics”

This study found that polymeric nanoparticles retained more minoxidil and facilitated superior drug permeation compared to lipid nanoparticles, although premature drug release affected formulation performance.

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Community Join

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community US FDA will now default to only one clinical trial for drug applications, will this accelerate the release of PP405 and other drugs in clinical trials?

13 upvotes 7 months ago

The FDA will now require only one clinical trial for drug approval, potentially speeding up the release of hair loss treatments like PP405. Pelage is expected to present full results of PP405 Phase 2a trials and move to Phase III in mid-2026.

community New baldness drug boosts hair coverage by up to 86% in six months

719 upvotes 3 months ago

A new extended-release oral minoxidil formulation claims to improve hair growth by maintaining steady blood levels, reducing side effects like hypotension, and potentially benefiting female hair loss. However, it is not considered groundbreaking as it builds on existing minoxidil treatments, and its effectiveness compared to current doses is debated.

community Jeff Vincent and his stealth drug growth stimulant is on track for Q1 2027

89 upvotes 1 month ago

A new hair growth drug claims to reverse severe hair loss without using minoxidil, finasteride, or hormone-altering drugs, but many are skeptical due to lack of evidence and concerns about misleading claims. The drug is expected to be released in early 2027, but its legitimacy is questioned.

community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

213 upvotes 1 year ago

PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

community Are these new hair loss treatments ever gonna release?

43 upvotes 6 months ago

Hair loss treatments like Breezula and PP405 are delayed, with approvals taking years, while existing treatments like minoxidil and finasteride remain popular. New treatments like Clascoterone and Veradermics are in trials, but high costs and lengthy approval processes slow their release.

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Learn

6 / 25 results

learn HMI-115

Experimental antibody that blocks the prolactin receptor

learn Microneedling

Technique that makes tiny punctures in the scalp with fine needles

learn Platelet-Rich Plasma

Concentrate of your own blood platelets, injected into the scalp

learn Pyrilutamide

Experimental topical anti-androgen, also known as KX-826

learn Stem Cell Factor

learn Baricitinib

Baricitinib: How did a drug for arthritis end up helping people regrow hair from alopecia areata? Baricitinib, an arthritis drug, was FDA-approved in 2022 for adults with severe alopecia areata after trials in which about a third of patients on 4 mg regained most scalp hair. It carries an FDA boxed warning, and regrowth is usually lost when it is stopped.

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Clinics

1 / 13 results

Hair Loss Treatments
Dr Joydeep Roy's Skin Clinic, New S.S.Medicos, (near Cachar high school), Malugram/ Drugs Corner, itkhola near Cachar CollegeSilchar, Assam · IN

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