Latanoprost Loaded in Polymeric Nanocapsules for Effective Topical Treatment of Alopecia
November 2020
in “
AAPS PharmSciTech
”
Research cited in this study
22 / 22 results
research LC-MS Bioanalytical Method for Simultaneous Determination of Latanoprost and Minoxidil in the Skin
This study developed an efficient LC-MS bioanalytical method to simultaneously quantify minoxidil sulphate and latanoprost in skin layers, supporting the formulation of topical treatments for androgenic alopecia.
research Dutasteride Nanocapsules for Hair Follicle Targeting: Effect of Chitosan-Coating and Physical Stimulus
This study demonstrates that massage significantly enhances the follicular targeting of dutasteride-loaded nanocapsules, increasing drug accumulation in hair follicles by up to 5 times.
research Effect of Physical Stimuli on Hair Follicle Deposition of Clobetasol-Loaded Lipid Nanocarriers
This study found that nanostructured lipid carriers with clobetasol propionate significantly enhance follicular drug delivery compared to commercial cream, and manual massage further doubles follicular retention.
research Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice
This study found that minoxidil nanoparticles increased drug delivery to hair follicles and improved hair growth more effectively in mice than conventional minoxidil formulations.
research New Drugs Under Investigation for the Treatment of Alopecias
This review explored the new and emerging treatments for androgenetic alopecia and alopecia areata, finding that JAK inhibitors show promise for alopecia areata, while advancements in stem-cell research may eventually lead to new and improved treatments for androgenetic alopecia.
research Minoxidil-Encapsulated Poly(L-Lactide-Co-Glycolide) Nanoparticles with Hair Follicle Delivery Properties Prepared Using Solvent Evaporation and Sonication
This study demonstrated that minoxidil-encapsulated PLLGA nanoparticles significantly increased minoxidil delivery to hair follicles compared to a minoxidil aqueous solution in mice.
research Latanoprost and Minoxidil: Comparative Double-Blind, Placebo-Controlled Study for the Treatment of Hair Loss
This study found that treatments with 5% minoxidil, with or without latanoprost, were effective in controlling hair loss and increasing hair strand count in patients with telogen effluvium or androgenic alopecia.
research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis found that minoxidil, finasteride, and low-level laser light therapy significantly improve hair growth in men with androgenetic alopecia, while minoxidil is also effective for women, compared to placebo.
research Solid Effervescent Formulations as a New Approach for Topical Minoxidil Delivery
This study found that a novel effervescent formulation significantly increased minoxidil sulphate accumulation in hair follicles and skin compared to a standard minoxidil solution.
research Preparation and Characterization of Minoxidil Loaded Nanostructured Lipid Carriers
This study found that nanostructured lipid carriers enhanced the skin penetration and retention of minoxidil compared to solid lipid nanoparticles, suggesting they could be a promising method for topical delivery.
research Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles
This study developed minoxidil sulphate-loaded chitosan nanoparticles that doubled drug delivery to hair follicles in vitro compared to a control solution, suggesting potential for improved alopecia treatment.
research Promising Alternative Clinical Uses of Prostaglandin F2α Analogs: Beyond the Eyelashes
This review discusses the potential applications of prostaglandin F2α analogs for certain types of alopecia and hypopigmentation, but reports no new experimental results.
research Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia
This study confirmed that a sulfotransferase enzyme test can effectively rule out 95.9% of nonresponders to 5% topical minoxidil for treating androgenetic alopecia.
research Comparison of the Efficacy of Niosomal Minoxidil with Conventional Minoxidil in the Treatment of Androgenetic Alopecia: A Randomized, Controlled, Double-Blind Clinical Trial
This study found that topical niosomal minoxidil significantly increased hair count and patient satisfaction compared to conventional minoxidil in men with androgenetic alopecia.
research Lipid Nanoparticles for Topical and Transdermal Application for Alopecia Treatment: Development, Physicochemical Characterization, and In Vitro Release and Penetration Studies
This study developed lipid nanoparticles for delivering minoxidil and finasteride to the dermis and hair follicles, showing stability and a desired prolonged release, though with low skin penetration levels.
research Squarticles as a Lipid Nanocarrier for Delivering Diphencyprone and Minoxidil to Hair Follicles and Human Dermal Papilla Cells
This research reported that squarticles, nanoparticles made from sebum-derived lipids, enhanced the follicular delivery and skin accumulation of diphencyprone and minoxidil, indicating effective drug deposition with reduced systemic absorption in alopecia treatment.
research Penetration Enhancer-Containing Vesicles as Carriers for Cutaneous Delivery of Minoxidil: In Vitro Evaluation of Drug Permeation by Infrared Spectroscopy
PEVs effectively deliver minoxidil through skin.
research A Randomized Double-Blind Placebo-Controlled Pilot Study to Assess the Efficacy of a 24-Week Topical Treatment by Latanoprost 0.1% on Hair Growth and Pigmentation in Healthy Volunteers with Androgenetic Alopecia
In this study, latanoprost significantly increased hair density in young men with mild androgenetic alopecia after 24 weeks, suggesting it may stimulate hair follicle activity and treat hair loss.
research Solid Lipid Nanoparticles Suspension Versus Commercial Solutions for Dermal Delivery of Minoxidil
This study found that solid lipid nanoparticles with minoxidil were as effective as commercial solutions for skin penetration and were non-corrosive, indicating potential for hair loss treatment.
research Selective Follicular Targeting by Modification of the Particle Sizes
This study found that medium-sized particles (643 and 646 nm) penetrated deeper into porcine hair follicles in vitro than smaller or larger particles, suggesting size-selective targeting within follicular sites.
research Latanoprost in the Treatment of Eyelash Alopecia in Alopecia Areata Universalis
This study found that latanoprost may be effective for treating eyelash alopecia areata, achieving cosmetically acceptable regrowth in 45% of patients.
research Minoxidil: Mechanisms of Action on Hair Growth
This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.
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This study found that encapsulating latanoprost in nanotransfersomes increased skin penetration and improved its cell proliferation effect in vitro, suggesting potential for treating hair growth disorders.
research In Vitro Evaluation of Topical Follicular Delivery of Minoxidil and Latanoprost Co-Entrapped in Lipid Nanocarriers
This study found that nanostructured lipid carriers significantly improved the targeted delivery of latanoprost and minoxidil to pilosebaceous units in porcine skin, with latanoprost showing notably higher accumulation.
research Nanostructured lipid carriers loaded with an association of minoxidil and latanoprost for targeted topical therapy of alopecia
This study suggests that a nanostructured lipid carrier formulation delivering minoxidil and latanoprost may enhance effectiveness and tolerability in treating alopecia by targeting hair follicles.
research Nanostructured Lipid Carriers Loaded with an Association of Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia
This study suggests that a nanostructured lipid carrier formulation of minoxidil and latanoprost may effectively target hair follicles and enhance drug penetration for alopecia treatment.
research Formulation and Evaluation of Finasteride Loaded Nanoparticles Based Topical Gel for the Management of drogenetic Alopecia
This study evaluated Finasteride-loaded nanostructured lipid carriers for topical use in treating androgenetic alopecia and found that these carriers offer sustained drug release and may reduce systemic side effects compared to oral administration.