TLDR PEVs effectively deliver minoxidil through skin.
The study evaluated the use of penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil. The results showed that the introduction of PE in the vesicular formulation led to deformable vesicles able to penetrate deeply in the skin with a formation of a drug depot. FTIR spectroscopy was used to analyze the vesicular formulations and to study the diffusion and distribution of MX in the skin. The study concluded that PEVs can be used as effective carriers for cutaneous delivery of minoxidil.
128 citations,
July 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.
85 citations,
January 2007 in “Journal of Drug Targeting” Liposomes better deliver minoxidil for hair loss treatment than niosomes.
397 citations,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
33 citations,
June 1995 in “Journal of Pharmaceutical Sciences” More ethanol increases minoxidil delivery, but too much lowers efficiency.
26 citations,
May 2012 in “Pharmaceutical Development and Technology” PEVs effectively deliver minoxidil through skin.
51 citations,
May 2010 in “Journal of Drug Targeting” Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.
128 citations,
July 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.
85 citations,
January 2007 in “Journal of Drug Targeting” Liposomes better deliver minoxidil for hair loss treatment than niosomes.
3 citations,
March 2005 in “Iranian Journal of Pharmaceutical Sciences”
